氨茶碱的热分解动力学研究  

Studies on the Kinetics of Thermal Decomposition of Aminophylline

作　　者：赵国燕[1] 郭金福[1] 黄东枫[1] 赵卉[1] 

机构地区：[1]安阳师范学院化学与化工学院,河南安阳455000

出　　处：《安阳师范学院学报》2012年第2期20-24,共5页Journal of Anyang Normal University

摘　　要：用TG-DTG(热重-微分热重)联用技术研究了氨茶碱片剂在氮气气氛中的热分解行为。首先运用普适法Kissinger和Ozawa法计算了氨茶碱片剂的表观活化能E和指前因子lnA,然后运用一般积分法Coats-Redfern法和Satava-Sestak法推测了主分解阶段的最佳热分解机理,推测出热分解机理为相边界反应,求出了热分解反应的表观活化能和指前因子。几种方法求得的表观活化能和指前因子的平均值分别为113.933KJ/mol,lnA为22.101(1/min).用malek法对所得结果进行了验证,进一步证明所得动力学参数和机理函数的正确性。The thermal decomposition kinetics of Aminophylline were investigated by means of TG–DTG（thermo gravimetry and differential thermo gravimetry） in nitrogen.The apparent activation energy E and the pre-exponential constant A were obtained by universal Kissinger method and Ozawa method.The best mechanism of main thermal decomposition is phase boundary reaction which predicted by Coat-Redfen integral equation and Satava-Sestak method.The apparent activation energy E and the pre-exponential constant A was calculated.The average apparent activation energy E and the pre-exponential constant A is 113.933KJ/mol and 22.101（1/min） respectively by the several methods.The accuracy were proved further by malek method.

关 键 词：氨茶碱 热分解 动力学 

分 类 号：O643[理学—物理化学]