以循证护理为基础的临床护理路径在结直肠癌FOLFOX化疗中的应用  

Application of evidence-based clinical nursing pathway to colorectal cancer patients receiving FOLFOX chemotherapy

作　　者：房敏[1] 张红弟[1] 蔡宏宇[1] 张景嫦[1] 苏玉梅[1] 苏晓霞[1] 李甜[1] 

机构地区：[1]广东医学院附属南山医院胃肠外科,广东深圳518052

出　　处：《护理学杂志》2012年第12期13-16,共4页

基　　金：广东省深圳市科技计划项目(201103309)

摘　　要：目的探讨循证护理理论指导下临床护理路径护理模式在结直肠癌FOLFOX化疗中的应用效果。方法将82例结直肠癌化疗患者随机分为观察组43例和对照组39例,对照组采用传统整体护理模式;观察组在循证护理理论指导下,提出目前结直肠癌FOLFOX化疗中存在的问题,然后寻找实证,制定临床护理路径并按照路径实施护理干预。结果观察组化疗所致的消化道反应、口腔炎、外周神经毒性反应程度显著轻于对照组,对护理工作的满意度显著高于对照组(P<0.05,P<0.01)。结论循证护理指导下的临床护理路径用于结直肠癌FOLFOX化疗,对确保化疗方案的实施,提高疗效和生活质量具有较好的效果。Objective To explore the effect of evidence-based clinical nursing pathway on patients receiving FOLFOX chemotherapy for colorectal cancer. Methods A total of 82 colorectal cancer patients receiving FOLFOX chemotherapy were randomized into an observation group of 43 and a control group of 39. Patients in the control group received traditional holistic nursing care. For the observation group, nurses put forward current problems lying in FOLFOX chemotherapy; they tried to retrieve the currently best evidence which answered the problems under the guidance of evidence-based nursing theory; they integrated the evidence to develop a clinical nursing pathway and put it into practice. Results The severity of chemotherapy-induced gastrointestinal reactions, mucositis, and peripheral nerve toxicity was milder, and patient satisfaction was higher, in the observation group than in the control group （P〈0.05,P〈0.01）. Conclusion The application of clinical nursing pathway developed based on the guidance of evidence- based nursing theory smoothes FOLFOX chemotherapy for patients with colorectal cancer, and improves the therapeutic effect and their quality of life.

关 键 词：结直肠癌 FOLFOX化疗 循证护理 临床护理路径 5-氟尿嘧啶 亚叶酸钙 奥沙利铂 

分 类 号：R473.6[医药卫生—护理学]