补充磷脂对大鼠腓肠肌钝挫伤后腓肠肌氧自由基反应和脂质过氧化反应的影响  

Recovery effectiveness of supplementary phospholipids on oxygen free radical reaction and lipid peroxidation of rat gastrocnemius ofter blunt trauma

作　　者：周静 董义俊 葛新发[3] 李可峰[3] 陈京来[3] 董贵俊[3] 

机构地区：[1]中国石油大学体育教学部,山东青岛266555 [2]47师预备役坦克团,吉林四平136500 [3]山东体育学院,山东济南250102

出　　处：《山东体育科技》2012年第3期30-33,共4页Shandong Sports Science & Technology

基　　金：山东省中青年科学家科研奖励基金(编号:2009BSB01066)

摘　　要：为了研究补充磷脂对大鼠腓肠肌钝挫伤恢复效果,采用重物下落装置建立急性骨骼肌钝挫伤模型,损伤后补充磷脂。在损伤后取样测定和计算腓肠肌SOD、CAT、GSH-Px活性及MDA含量变化。与自然愈合组比较结果发现,损伤后第2-10d,补充磷脂能显著提高腓肠肌SOD、GSH-Px活性,显著降低MDA含量,对CAT活性影响未出现显著变化。因此,补充磷脂能明显提高大鼠急性骨骼肌钝挫伤后的腓肠肌中SOD、GSH-Px活性,降低腓肠肌中MDA含量,对于清除大鼠受损腓肠肌氧自由基,加快消除损伤后发生的脂质过氧化反应,降低脂质过氧化水平,提高急性骨骼肌钝挫伤恢复效果具有促进作用。In order to explore the recovery effect of supplementary phospholipids on rat gastrocnemius after blunt injury, the acute skeletal muscle contusion was produced by heavy objects dropping devices. Subcutaneous feeding or blank control were performed respectively with each group. The muscles were sampled after contusion, and then the muscle contractive strength and relaxation were measured while superoxide dismutase and malondialdehyde were determined. From the second day to the tenth day, complement phospholipids could markedly improve the activities of SOD, GSH - Px, and significantly reduce the content of MDA and affect CAT activity insignificantly. Therefore, supplementary phospholipids could improve SOD, GSH- Px activity and reduce the MDA content after the rat acute gastrocnemius blunt injury, facilitate and promote clearing free radical damage muscles restoration. Supplementary phospholipids could significantly muscle contusion. improve the healing of injured muscles in rat acute skeletal

关 键 词：腓肠肌 磷脂 钝挫伤 氧自由基反应 脂质过氧化反应 

分 类 号：G807.4[文化科学—体育训练]