术后脓毒症患者早期肠内营养的应用  

Clinical observation on intermittent renal replacement therapy in severe acute panreatitis

作　　者：曾丽萍[1] 何清[1] 叶华[1] 唐启彬[2] 孙健[2] 王捷[2] 

机构地区：[1]中山大学孙逸仙纪念医院SICU,广州510120 [2]中山大学孙逸仙纪念医院肝胆外科,广州510120

出　　处：《岭南现代临床外科》2012年第4期338-340,共3页Lingnan Modern Clinics in Surgery

基　　金：广东省自然科学基金(10151008901000138)

摘　　要：目的探讨早期肠内营养与延迟肠内营养对术后脓毒症患者预后的影响。方法回顾性分析7年内我院ICU收治腹部手术后脓毒症患者的临床资料。其中20例实施早期肠内营养(EEN),32例行肠外营养(PN)+延迟肠内营养(DEN)。分析两组患者机械通气率、持续性肾替代治疗(CRRT)治疗时间、住ICU时间及住院死亡率的差异。结果与DEN组比较,EEN组机械通气率低、CRRT治疗时间及住ICU时间缩短;住院死亡率无显著差异。结论肠内营养是脓毒症患者重要的营养支持方式,早期肠内营养安全可行,可部分改善临床预后。Objective To discuss the effects of early enteral nutrition （EEN） and delayed enteral nutrition （DEN） in patients with sepsis after abdominal surgery. Methods The clinical data of 52 cases with postoperative sepsis were analyzed retrospectively. Patients were divided into two groups based on whether enteral EEN was initiated within 48 hours after ICU admission. Mortality, mechanical ventilation rates, time for continuous renal replacement therapy （CRRT） and length of ICU stay were compared among two groups. Results EEN could lower mechanical ventilation rate, and reduce the time of CRRT and the length of ICU stay. There were no differences in the hospital mortality between the groups. Conclusion Enteral nutrition therapy plays an important role in the management of postoperative patients with sepsis. Early EN could be successfully delivered for that population, with improved outcomes partly.

关 键 词：脓毒症 肠内营养 ICU 

分 类 号：R459.3[医药卫生—治疗学]