脑钠肽、肌钙蛋白Ⅰ、超敏C-反应蛋白在急性心肌梗死中的临床意义  

Clinical Significance of Brain Natriuretic Peptide combined with Cardiac Troponi Ⅰ and Hypersensitive C-reactive protein in Acute Myocardial Infarction

作　　者：崔杰西[1] 程训民[1] 马燕[1] 王广川[2] 

机构地区：[1]安徽省淮北市人民医院检验科,安徽淮北235000 [2]安徽省淮北市人民医院心内科,安徽淮北235000

出　　处：《吉林医学》2012年第19期4052-4054,共3页Jilin Medical Journal

摘　　要：目的:探讨急性心肌梗死(AMI)患者血浆B型钠尿肽(BNP)、肌钙蛋白Ⅰ(cTnⅠ)、超敏C-反应蛋白(Hs-CRP)检测的临床意义。方法:选取急性心肌梗死患者50例,正常健康对照组30例,分别检测BNP、cTnⅠ、Hs-CRP的浓度,并进行比较和相关分析,分析其与急性心肌梗死的关系。结果:①AMI组血浆BNP、cTnⅠ、Hs-CRP的结果与健康对照组相比较,显著升高,差异有统计学意义(P<0.01)。②对AMI组BNP、cTnⅠ、Hs-CRP进行相关性分析,结果表明BNP、cTnⅠ、Hs-CRP具有高度的正相关性。结论:血浆BNP和cTnⅠ、Hs-CRP水平在AMI患者中显著升高,联合检测血浆BNP、cTnⅠ、hs-CRP水平对AMI的辅助诊断、疗效观察及预后判断具有重要价值。Objective To explore the clinical significance of brain natriuretie poptide,cardiac troponin Ⅰ and hypersensitive C - reac- tive protein in acute myocardial infarction. Method The plasma levels of brain natriuretic peptide, cardiac troponin I and hypersensitive C - reactive protein parallelly detected in 50 cases of acute myocardial infarction group and other 30 cases of the contrasting group. The eontras- rive analysis and correlation of them were conducted and analyzed the relationship with acute myocardial infarction. Results （1）he levels of BNP,cTn Ⅰ ,Hs - CRP in acute myocardial infarction group were significantly higher than those in the contrasting group（P 〈0. 01 ）. （2）In acute myocardial infarction group,significant positive correlation was found between plasma BNP,cTn Ⅰ ,and Hs -CRP. Conclusion Brain natriuretic peptide, cardiac troponin I and hypersensitive C - reactive protein combined detection of acute myocardial infarction（AMI） pre- dict favorable diagnosis and prognosis.

关 键 词：脑钠肽 肌钙蛋白Ⅰ 超敏C-反应蛋白 急性心肌梗死 

分 类 号：R542.22[医药卫生—心血管疾病]