用健康危险度评价方法探讨溶纤剂的卫生标准  

Study on the standard of 2-ethoxyethanol with health risk assessment method

作　　者：周素梅[1] 高星[1] 

机构地区：[1]北京市劳动卫生职业病防治研究所,北京100020

出　　处：《中国工业医学杂志》2000年第2期80-83,共4页Chinese Journal of Industrial Medicine

摘　　要：目的　利用健康危险度评价方法探讨溶纤剂的卫生标准。方法　根据现场空气监测和职业性健康检查及动物实验结果 ,利用健康危险度评价方法 ,推算出溶纤剂卫生标准。结果　现场测定浓度估算出的每日暴露量(EED) 1 7mg/kg与动物实验推算出的参考剂量 (RfD) 2 0mg/kg基本接近。推算出的 2 EE时间加权平均浓度 2 1mg/m3与美国卫生标准 19mg/m3接近。结论　利用健康危险度评价方法 ,为制定卫生标准提供可靠的依据是可行的。Objective To study the hygiene standard of 2 etheoxyethanol(2 EE)with health risk assessment method.Method According to results of air monitoring in working places,occupational health examination and animal experiment,using health risk assessment method,the hygiene standard of 2 etheoxyethand was projected.Results The projected exposure dose per day(EED)from the air concentration of working place was 1 7mg/kg,quite near the reference dose(RfD)——2 0mg/(kg·d)projected from the animal experiment.The projected TWA of 2 EE(21mg/m 3)also approaches the hygiene standard of 2 EE in USA(19 mg/m 3).Conclusion Health risk assessment may be a reliable method for the preparation of hygiene standard.

关 键 词：健康危险度评价 溶纤剂 卫生标准 

分 类 号：R134.1[医药卫生—劳动卫生]