辨证分型论治葡萄膜炎及其对免疫功能的影响  

An observation of on immune functions in treatment of uveitis with bianzhenfenxing

作　　者：詹宇坚[1] 古继红[2] 王燕[1] 王舜杏[1] 彭耀崧[1] 詹前贤[1] 关国华[1] 

机构地区：[1]广州中医药大学第一附属医院眼科,广州510405 [2]广州中医药大学基础医学院

出　　处：《中国中医眼科杂志》2000年第2期77-80,共4页China Journal of Chinese Ophthalmology

基　　金：国家中医药管理局科研基金课题!(基金号922901)

摘　　要：目的　观察中药治疗葡萄膜炎的效果及其对免疫功能的影响。方法　葡萄膜炎患者44例按辨证分为热毒炽盛和肝肾阴虚两型 ,分别使用中药消炎一号方和消炎二号方治疗 ,并分别于治疗前后检测T细胞亚群、免疫球蛋白、补体和IL -2的变化。结果　热毒炽盛型患者OKT4、OKT4/OKT8、IL -2和IgM治疗后比治疗前下降 (P <0 0 5或 0 0 1 )。肝肾阴虚型患者治疗后OKT8、IL -2和补体C3升高 (P <0 0 5 ) ;OKT4/OKT8和IgG治疗后下降 (P <0 0 1 )。结论　消炎一号方和消炎二号方分别具有促进免疫和抑制免疫作用 。OBJECTIVE To observe the effect of Chinese herbs on treatment in patients with uveitis and the changes of immune functions METHODS We observed forty-four patients with uveitis were divided into reduzhisheng(热毒炽盛) type and ganshenyinxui (肝肾阴虚)type They were treated with anti-inflammation decoction I and II respectively T cell subgroups, immune globulin, complements and IL-2 were estimated before and after treatments in the patients RESULTS OKT 4, OKT 4/OKT 8, IL-2 and IgM were decreased after treatment in reduzhisheng type ( P <0 05 or 0 01) OKT 8、IL-2 and complements C 3 were increased ( P <0 05), and OKT 4/OKT 8 and IgG were decreased ( P <0 01) in ganshenyinxui type after treatment CONCLUSIONS Anti-inflammation decoction I and II could regulate immune functions for immunoenhancement and immunosuppression both

关 键 词：葡萄膜炎 免疫 辨证分型 中医药疗法 

分 类 号：R276.73[医药卫生—中医五官科学]