男男同性性行为者HEV感染危险因素研究  

Survey on risk factors of HEV infection among man who have sex with man

作　　者：韩凌飞[1] 文育锋[1] 程险峰[2] 朱明[2] 陈道利[2] 周术容[2] 

机构地区：[1]皖南医学院预防医学系,安徽芜湖241001 [2]马鞍山市疾病预防控制中心检验科,安徽马鞍山243000

出　　处：《中华疾病控制杂志》2012年第7期586-589,共4页Chinese Journal of Disease Control & Prevention

基　　金：马鞍山市科技计划项目(2008-40)

摘　　要：目的了解男男同性性行为人群(man who have sex with man,MSM)戊型肝炎病毒(hepatitis E virus,HEV)感染情况,并分析MSM高危行为方式与HEV感染之间的关系,为开展有针对性的开展健康教育和行为干预提供依据。方法采用统一设计的调查问卷进行调查,问卷内容包括基本人口学特征、性行为特征及安全套使用情况,用酶联免疫吸附法(enzyme-linked immunosorbent assay,ELISA)检测HEV抗体,采用Logistic回归分析戊型肝炎感染的危险因素。结果参与调查的63名MSM对象中,14名抗HEV-IgG阳性,阳性率为22.2%。多因素分析显示,近6个月内发生肛交性行为(OR=11.924,95%CI:1.783～79.730)、男男同性恋(OR=7.401,95%CI:1.231～44.481)、职业为工人和农民(OR=8.131,95%CI=1.383～47.813)是HEV感染的危险因素。结论 MSM人群的高危性行为可能是戊型肝炎传播的危险因素。Objective To investigate hepatitis E virus（HEV） infection prevalence among man who have sex with man（MSM）,analyze the relationship between high-risk behaviors and HEV infection,and to provide the strategies of sexual health education and behavioral intervention.Methods The self-administration questionnaire of sexual characteristics and condom use was conducted in MSM.The HEV antibodies were tested with enzyme-linked immunosorbent assay（ELISA）.The risk factors of HEV infection was analyzed by using Logistic regression.Results HEV antibodies positive rate of MSM was 22.2%.The results of multivariate Logistic analysis indicated that anal sex in last six months（OR=11.924,95%CI：1.783-79.730）,homosexual（OR=7.401,95%CI：1.231-44.481） and occupation with farmer and worker（OR=8.131,95%CI：1.383-47.813） were risk factors of HEV infection.Conclusions The high risk sexual behaviors may be the risk factors of HEV infection among MSM.

关 键 词：性行为 戊型肝炎病毒属 危险因素 

分 类 号：R512.65[医药卫生—内科学]