电针对老年阿尔茨海默病大鼠额叶神经递质含量的影响  

Influence of Electric Acupuncture on DU20 and KI1 on Contents of Neurotransmittre in Frontal Lobe of Alzheimers Disease

作　　者：王莉[1] 胡卡明[2] 高怀云[3] 

机构地区：[1]成都市中西医结合医院,四川成都610016 [2]成都中医药大学附属医院针灸科,四川成都610072 [3]成都中医药大学针灸推拿学院,四川成都610075

出　　处：《成都中医药大学学报》2012年第2期25-26,30,共3页Journal of Chengdu University of Traditional Chinese Medicine

基　　金：四川省教育厅资助项目(编号:09ZA030)

摘　　要：目的:探讨电针"百会、涌泉"对老年阿尔茨海默病大鼠额叶神经递质含量的影响。方法:采用Morris水迷宫通过对老年大鼠及青年大鼠逃避潜伏期的比较进行筛选,将筛选出的大鼠归为正常老年组、电针组、模拟组。电针组抓取固定后百会、涌泉施以电针。余下两组给予同样程度抓取,固定,但不施电针。治疗结束后分离额叶进行神经递质检测。结果:电针组额叶神经递质含量较模型组有明显升高,(P<0.05或P<0.001)。结论:电针百会、涌泉能明显改善老年AD大鼠的额叶神经递质含量。Objective： To discuss whether electric acupuncture on DU20 and KII will have effect on content in frental lobe of old Alzheimer＇s rats. Methods： Morris water maze was used to screen old rats through comparing with the escape latency of young rats. The old rats will be divided into the health rats group electric acupuncture group and simulation group. Rats in the elec- tric acupuncture group was treated on DU 20 and KI1 after being fastened, while rats in the other two group were only fastened without any treatment. All the old rats will be separated frontal lobe to test neurotransmitter content. Results： Neurotransmitter content of frontal lobe in the electric group was obviously improved with model group （P 〈 0. 05orP 〈 0. 001 ）. Conclusion： Electric acupuncture on DU20 and KI1 could significantly improve neurotransmitter content of AD old rats＇ frontal lobe.

关 键 词：电针 神经递质 AD大鼠 

分 类 号：R245.33[医药卫生—针灸推拿学] R277.7[医药卫生—中医临床基础]