振荡萃取-GC-MS测定烟用添加剂中高关注物质二甲苯麝香  

Determination of Substances of Very High Concern Musk Xylene in Tobacco Additives by Oscillation Extraction-GC-MS

作　　者：耿永勤 陈建华[1] 黄海涛[1] 缪恩铭 师艳萍[2] 徐济仓[1] 李雪梅[1] 

机构地区：[1]云南烟草科学研究院,昆明市科医路41号650106 [2]红云红河烟草(集团)有限责任公司,昆明市红锦路181号650202

出　　处：《光谱实验室》2012年第4期2514-2518,共5页Chinese Journal of Spectroscopy Laboratory

基　　金：云南中烟工业有限责任公司资助项目(2011JC02;2012JC05)

摘　　要：建立了振荡萃取-气相色谱-质谱法测定烟用添加剂中二甲苯麝香的方法,样品采用超纯水分散后,加入D_(15)-二甲苯麝香作为内标物,用环己烷振荡萃取并离心,取上层有机相,浓缩干燥后采用GC/MS选择离子监测进行定量分析。二甲苯麝香的检出限为0.04μg/g,定量限为0.13μg/g。在0.15、0.3、0.5μg/g3个添加水平范围内的平均回收率(每个添加浓度平行测定6次)为84.1%—91.4%,相对标准偏差(RSD)值均小于10%。该方法适用于对烟用添加剂中高关注物质二甲苯麝香的监测自查工作。A method for the determination of musk xylene in tobacco additives by oscillation extraction-GC-MS was developed.The samples were dispersed by ultrapure water,then adding D15-xylene musk as the internal standard substances,and were extracted and oscillated by cyclohexane.The extract was centrifuged,and the upper solution was concentrated and dried to quantificationally analyze by GC-MS selective ion monitoring.The limit of detection（LOD） for musk xylene was 0.04μg/g and the limit of quantitation（LOQ） was 0.13μg/g.The average recoveries at the three levels of 0.15,0.3,0.5μg/g were 84.1%-91.4%and the RSDs were less than 10%.The method is adapted to the monitoring of substance of very high concern musk xylene in tobacco additives.

关 键 词：振荡萃取 气相色谱-质谱法 烟用添加剂 二甲苯麝香 

分 类 号：O657.63[理学—分析化学]