ICU革兰阴性杆菌肺炎病原菌耐药性调查  

Antibiotics resistance of gram-negative bacilli causing pneumonia in ICU

作　　者：林建军 

机构地区：[1]宁波市象山第一人民医院检验科,浙江宁波315700

出　　处：《中华医院感染学杂志》2012年第14期3175-3176,3182,共3页Chinese Journal of Nosocomiology

摘　　要：目的探讨ICU患者革兰阴性杆菌肺炎病原菌的耐药性特点,为临床医师合理使用抗菌药物提供参考依据。方法细菌培养按照《全国临床检验操作规程》进行;药敏试验采用K-B法。结果主要革兰阴性杆菌依次为铜绿假单胞菌占31.5%、肺炎克雷伯菌占20.8%、鲍氏不动杆菌占18.3%、嗜麦芽寡养单胞菌占11.1%、大肠埃希菌占9.1%;主要革兰阴性均显示多药耐药性,耐亚胺培南铜绿假单胞菌和鲍氏不动杆菌检出率分别为12.9%、16.7%。结论临床医师应合理使用抗菌药物,有效预防与控制ICU患者医院获得性肺炎。OBJECTIVE To approach the antibiotic resistance of gram-negative bacilli causing pneumonia in ICU and provide the reference for clinically reasonable use of antibiotics.METHODS Referring to national guide of clinical laboratory procedures,the strains were isolated and cultured.The antibiotic susceptibility testings were performed by K-B methods.RESULTS Gram-negative bacilli were mostly comprised of Pseudomonas aeruginosa（31.5%）,Klebsiella pneunmoniae（20.8%）,Acinetobacter baumannii（18.3%）,Stenortrophomonas maltophilia（11.1%）,and Escherichia coli（9.1%）;the common gram-negative bacilli showed multi-resistance,the detection rates of imipenem-resistant P.aeruginosa and A.baumannii were 12.9% and 16.7%,respectively.CONCLUSION The clinician should use the antibiotics rationally in order to effectively prevent and control the hospital-acquired pneumonia in ICU patients.

关 键 词：ICU 医院获得性肺炎 革兰阴性杆菌 耐药性 感染 危险因素 

分 类 号：R378[医药卫生—病原生物学]