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作 者:郭齐[1,2] 田昕[2] 杨傲然 吴丹[1] 朱晓奕[4] 周亚平[4]
机构地区:[1]江苏大学基础医学与医学技术学院,江苏镇江212013 [2]北京中医药大学基础医学院,北京100029 [3]北京中西医结合医院,北京100039 [4]江苏大学附属医院中医科,江苏镇江212013
出 处:《中华中医药学刊》2012年第7期1490-1491,共2页Chinese Archives of Traditional Chinese Medicine
基 金:国家自然科学基金资助项目(21006041);江苏大学高级专业人才科研启动基金资助项目(11JDGO74);江苏省大学生实践创新训练计划项目(0731)
摘 要:目的:观察降脂康胶囊对高脂血症患者的临床疗效,证实其降脂作用。方法:随机选取120例高脂血症患者,分为治疗组与对照组各60例,治疗组予降脂康胶囊口服,对照组予脂必妥胶囊口服,疗程为12周。结果:治疗组能有效改善患者的临床症状,症状改善总有效率为90%,明显优于对照组。治疗组降低血清TG和LDL-C含量的疗效优于对照组(P<0.05)。两组降低血清TC含量的疗效相当,而升高血清HDL-C含量的疗效均不显著。结论:降脂康胶囊治疗高脂血症的疗效确切,并能显著减少临床症状和体征,未见明显的不良反应,具有良好的临床应用前景。Objective:To observe the therapeutic effects of Jiangzhikang Capsules on patients with hyperlipidemia.Methods:120 patients with hyperlipidemia were randomly divided into a treatment group in which 60 cases were treated with Jiangzhikang Capsules and a control group in which 60 cases treated with Zhibituo(capsules for decreasing the hyperlipidemia).The patients in both groups orally took drug for 8 weeks as a course.After treatment,the changed symptoms,the therapeutic effect and the changed hyperlipidemia level were observed in both groups.Results:The total effective rate of treatment group was better in relieving symptoms(90%)than that of control group(60%)(P0.01).As compared with the control group,the treatment group markedly decreased the TG and LDL-C levels(P〈0.05).But no significant difference was found in increasing HDL-C level in both groups.Conclusion:Jiangzhikang Capsules had definite therapeutic effect on patients with hyperlipidemia.No toxic side-effects and adverse reactions were found during the treatment and in the follow-up visit.
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