急性肺栓塞43例患者诊治分析  

Diagnosis and treatment of acute pulmonary embolism: an analysis of 43 cases

作　　者：何磊[1] 李怡霖[1] 孟爱果[1] 刘用格[1] 

机构地区：[1]邢台市人民医院心脏内科,湖北邢台054000

出　　处：《心血管病防治知识（学术版）》2012年第4期25-28,共4页Prevention and Treatment of Cardiovascular Disease

基　　金：邢台市科学技术研究与发展计划2012ZC086

摘　　要：目的总结43例急性肺栓塞(Acute Pulmonary Embolism,APE)患者的临床特点和治疗经验。方法对2010年8月-2011年12月住院的APE患者的易患因素、临床表现、实验室检查及治疗转归进行回顾性分析。结果(1)60-70岁APE患者所占比例最高,多数患者存在危险因素;(2)APE患者最常见症状为呼吸困难,心电图以胸前导联T波倒置最为常见,心型脂肪酸结合蛋白(H-FABP)升高为23.3%,与临床不良事件相关;(3)43例患者中有6例行溶栓治疗,无严重出血事件。结论APE临床表现多样,发病与易患因素有关;H-FABP升高患者预后不良,可作为新的危险分层标记物。Objective To summarize the clinical characteristics and therapeutic experience of acute pulmonary embolism （APE） in 43 patients. Methods Retrospective analysis of risk factors, clinical manifestations, laboratory examinations, and treatment outcomes was performed on patients with APE who were admitted to our hospital from August 2010 to December 2011. Results The age group of 60-70 yrs accounted for the highest proportion of patients with APE, and most of them had the risk factors related to APE. Dyspnea was the most common symptom and precordial T-wave inversion of electrocardiogram was most prevalent in APE patients. Heart- type fatty acid-binding protein （H-FABP） increased 23.3%, which was associated with clinical adverse events. Among the 43 patients, 6 cases receiving thrombolytic therapy showed no serious bleeding events. Conclusion Clinical manifestations are diverse in APE patients. The onset of APE is associated with its risk factors. The prognosis of patients with increased H-FABP is bad, so H-FABP can be used as a new risk stratification marker.

关 键 词：急性肺栓塞 心型脂肪酸 危险分层 

分 类 号：R563.5[医药卫生—呼吸系统]