N-(末端三甲基硅苄基甘氨酸肽链)-2,3-萘二甲酰亚胺的光诱导单电子转移成环反应  

Photoinduced Single Electron Transfer Cyclization Reaction of N-(Amidosilane terminated polybenzylglycine peptide chain)-2,3-naphthalimide

作　　者：金英学[1] 王家昌[1] 岳群峰[1] 曲凤玉[1] 魏树权[1] 谭广慧[1] 

机构地区：[1]哈尔滨师范大学化学化工学院,哈尔滨150025

出　　处：《有机化学》2012年第7期1290-1295,共6页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.20972036);国家自然科学基金(No.21171045);黑龙江省自然科学基金(No.B200913);黑龙江省高校科技创新团队建设计划项目(No.2011TD010)~~

摘　　要：以苄基甘氨酸为起始物合成了新型分子内给受电子体系N-(末端三甲基硅苄基甘氨酸肽链)-2,3-萘酰亚胺(1).1在MeOH-30%H2O中发生光诱导单电子转移反应,以很高的区域选择性生成新型环苄基甘氨酸肽化合物2.所有新化合物均经MS和NMR确定结构.Benzylglycine was used as starting material for the synthesis of novel intramolecular electron donor-accepter sys- tem N-（amidosilane terminated polybenzylglycine peptide chain）-2,3-naphthalimide （1）. 1 could undergo a photoinduced sin- gle electron transfer cyclization reaction in MeOH-30% H20 solvent to provide novel cyclopolyglypeptides 2 in high regioselectivity. The structures of all the new compounds were characterized by MS and NMR techniques.

关 键 词：光诱导 单电子转移 2 3-萘二甲酰亚胺 苄基甘氨酸肽链:环肽 

分 类 号：O629.72[理学—有机化学]