N-长链胆酸酰胺的合成  

Synthesis of N-long-chain alkyl cholic amide

作　　者：王立中[1] 卞小琴[1] 周兰香[2] 李双双[2] 李广州[1] 王存德[2] 

机构地区：[1]泰州职业技术学院环境与化学工程系,江苏泰州225300 [2]扬州大学化学化工学院,江苏扬州225002

出　　处：《化学工程师》2012年第7期8-10,72,共4页Chemical Engineer

基　　金：江苏省高等学校大学生实践创新训练计划项目(No.1125633jg1);江苏青蓝工程项目和泰州职业技术学院科研项目(No.TZK201001-2)

摘　　要：本文研究了具有长脂链胆酸基非离子型表面活性剂的合成，以商品化胆酸和一系列的长链伯胺（C12-C18）为原料，经过多步反应获得了N-长链烷基胆酸酰胺。目标化合物结构经IR，^1H—NMR，^13C—NMR，LC-MS等表征确证，同时，对其表面活性进行了初步研究。The long-chain alkyl cholic amide derivatives were synthesized using bile acid and long-chain alkyl amines as starting materials. All these structures were confirmed by IR, ^1H-NMR,^13C-NMR,LC-MS and their tensionmetrie property was tested. The results were indicated that the long-chain alkyl induced in the cholic acid increased its hydrophobic property.

关 键 词：三甲酰氧基胆酸酰氯 三甲酰氧基胆酸酰胺 胆酸酰胺 合成 

分 类 号：O629.22[理学—有机化学]