糖尿病和非糖尿病患者冠状动脉粥样硬化病变的比较研究  

Assessment of Coronary Artery Disease by Computed Tomography in Patients with and Without Diabetes Mellitus

作　　者：黄晗[1] 何雪松[1] 王锋[1] 李伟[1] 

机构地区：[1]中航工业哈尔滨二四二医院,黑龙江哈尔滨150066

出　　处：《航空航天医学杂志》2012年第7期788-790,892,共4页Journal of Aerospace medicine

摘　　要：目的:比较在冠状动脉CT检查中所显示的糖尿病和非糖尿病患者冠状动脉粥样硬化病变的情况。方法:96名糖尿病患者(平均年龄:64±10岁;男性:52例)和202名非糖尿病患者(年龄:61±13岁;男性:120例),应用冠状动脉CT检查有无冠状动脉病变及病变程度。同时利用钙化积分来评估冠状动脉钙化情况。结果:与非糖尿病患者相比,糖尿病患者冠状动脉有较多部位动脉粥样硬化病变(4.1±4.2 vs 2.1±3.0;P<0.000 1);冠状动脉钙化积分>400的比例较高(P<0.001);阻塞性冠状动脉病变比例较高(37%vs 18%;P<0.000 1),而正常的冠状动脉的比例较低(20%vs 42%;P<0.000 1)。结论:糖尿病患者的冠状动脉粥样硬化负荷较高。Objective：To compare the coronary atherosclerotic burden in patients with and without type-2 diabetes using CT Coronary Angiography（CTCA）.Methods：And Materials 96 diabetic（mean age：64±10 years;male：52） and 202 nondiabetic patients（mean age：61±13 years;male：120） without a history of coronary artery disease（CAD） underwent CTCA.The per-patient number of diseased coronary segments was determined and each diseased segment was classified.Coronary calcium scoring（CCS） was assessed too.Results：Diabetics showed a higher number of diseased segments（4.1±4.2 vs 2.1±3.0;P0.000 1）;a higher rate of CCS400（P0.001）,obstructive CAD（37% vs 18% of patients;P0.000 1）,and fewer normal coronary arteries（20% vs 42%;P0.000 1）,as compared to nondiabetics.Conclusions：Diabetes was associated with higher coronary plaque burden.

关 键 词：糖尿病 冠状动脉疾病 CT冠状动脉血管造影术 

分 类 号：R587.1[医药卫生—内分泌]