临床相关的脊髓损伤动物模型新进展  

New progress of clinically relevant spinal cord injury models

作　　者：吴超[1] 余上斌[2] 

机构地区：[1]华中科技大学同济医学院 [2]华中科技大学 同济医学院基础医学院,湖北武汉430030

出　　处：《基础医学与临床》2012年第8期968-970,共3页Basic and Clinical Medicine

基　　金：国家自然科学基金(81070937;81172387);2010年国家大学生创新性实验项目计划(101048717)

摘　　要：自1911年首个脊髓损伤动物模型建立以来,相继出现切割损伤型、牵拉损伤型、压迫损伤型和缺血损伤型等模拟临床不同环境的脊髓损伤动物模型。迄今,这些模型在建立过程中不断融入许多新技术:计算机控制的精确打击、定位下的精准切割,数字化的牵拉器及符合生物力学的脊髓压迫器等。科学技术的发展促进了脊髓损伤动物模型更加贴近不同的临床状态。Since the first spinal cord injury model was established in 1911, various models, which are similar to clinical situations, have been developed. These were transaction, retraction, compression and vascular exclusion. Nowadays, many new technologies, such as computer-controlled accurate strike, guided precision surgical cut, digital retractor and biomechanical compression device, have been applieated in modeling. With development of science and technology, a variety of models may well simulate clinical states.

关 键 词：脊髓损伤 动物模型 

分 类 号：R651.2[医药卫生—外科学] R-332[医药卫生—临床医学]