^(18)F-FDG和^(11)C-choline PET/CT诊断前列腺良恶性病变的影响因素研究  

The influence factor of ^(18)F-FDG and ^(11)C-choline PET/CT for diagnosing prostate neoplasms

作　　者：陈翼[1,2] 彭艳梅[2] 洪愉[2] 徐昕明[2] 冯盼盼[1] 全显跃[1] 

机构地区：[1]南方医科大学附属珠江医院影像诊断中心,广东广州510000 [2]成都军区昆明总医院PET-CT中心,云南昆明650032

出　　处：《医学影像学杂志》2011年第10期1526-1529,共4页Journal of Medical Imaging

摘　　要：目的:探讨18F-FDG(18F-脱氧葡萄糖)和11 C-choline(11 C-胆碱)PET/CT显像诊断前列腺良恶性病变的影响因素,以提高PET/CT对前列腺病变的诊断价值。方法:选择可疑前列腺病变患者55例为研究对象,年龄57～82岁,28例为前列腺癌,转移程度不一;其余为前列腺良性病变。所有患者均行全身18 F-FDG和11 C-choline PET/CT检查,分析18 F-FDG和11 C-choline标准摄取值(SUV)与前列病变患者的年龄及病理类型的相互关系和意义。结果:55例前列腺病变患者,18F-FDG和11 C-choline标准摄取值与患者的年龄无统计学差异(P>0.05),18 F-FDG标准摄取值与患者的病理类型亦无统计学差异(P>0.05),而11 C-choline标准摄取值与患者的病理类型有统计学差异(P<0.05)。结论:前列腺病变患者的病理类型是影响11 C-choline标准摄取值的重要因素,11 C-choline PET/CT鉴别诊断前列腺良恶性病变具有重要的价值和意义。Objective：To evaluate the influence factor of F-FDG and C-choline PET/CT for diagnosing prostate neoplasms. Methods：To choose 55 patients with prostate neoplasms as study target, the age from 57 to 82 years old. In all cases, 28 cases were prostate cancer, others were benign prostate neoplasms. 18 F-FDG and H C-choline PET/CT were per-formed on 55 patients. To study the affect of SUV of 18 F-FDG and H C-choline with age and pathology of all patients with prostate neoplasms. Results： From 55 cases, the SUV of 18 F-FDG and 11 C-choline were no ststistics difference with age （ P 〉0.05）, the SUV of 18 F-FDG was no ststistics difference with pathology of prostate neoplasms （ P 〉0.05）, otherwise, the SUV of n C-choline was clearly ststistics difference with pathology of prostate neoplasms （ P 〈0.05）. Conclusion： The pathology of prostate neoplasms was important influence factor for SUV of n C-choline, and the n C-choline PET/CT for prostate neoplasms has confirmed the high diagnostic effectiveness and demonstrates that it has a great influence on the clinical management of patients with prostate necoplasms.

关 键 词：18F-脱氧葡萄糖 11C-胆碱PET/CT 诊断 前列腺病变 影响因素 

分 类 号：R697[医药卫生—泌尿科学] R814.42[医药卫生—外科学]