治疗偏头痛药物那拉曲坦的药理与临床研究  

Progress in pharmacological and clinical studies of naratriptan for migraine

作　　者：刘宇[1] 刘东[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院药剂科,湖北武汉430030

出　　处：《中国新药与临床杂志》2012年第7期373-376,共4页Chinese Journal of New Drugs and Clinical Remedies

摘　　要：那拉曲坦是高选择性5-羟色胺(5-HT1D/1B)受体激动剂,临床用于偏头痛的治疗,本文结合现有文献,对其药理作用、药动学、临床研究、安全性等内容进行了综述。Naratriptan is a highly selective agonists at the 5-HTID and 5-HT1B receptors for migraine. In this review, the pharmacological mechanism, pharmacokinetics, clinical trials, safety of naratriptan were summarized.

关 键 词：那拉曲坦 偏头痛 临床试验 安全 

分 类 号：R971[医药卫生—药品]