消风止痒颗粒联合依巴斯汀治疗慢性荨麻疹44例临床观察  

Clinical Observation of Xiaofengzhiyang Granules combined with Ebastine in Treatment of Chronic Urticaria

作　　者：李占国[1] 夏永华[1] 付丹丹[1] 郭金梅[1] 李素娟[1] 李敏[1] 刘冬[1] 田中伟[1] 

机构地区：[1]新乡医学院第一附属医院皮肤科,河南卫辉453100

出　　处：《中国皮肤性病学杂志》2012年第8期767-768,共2页The Chinese Journal of Dermatovenereology

基　　金：河南省卫生科技创新型人才工程专项经费(201004159)

摘　　要：目的观察消风止痒颗粒联合依巴斯汀治疗慢性荨麻疹的疗效及安全性。方法 86例慢性荨麻疹患者随机分为两组,治疗组口服消风止痒颗粒12g,3次/d,联合依巴斯汀片10mg,1次/d,对照组仅用依巴斯汀片,用法同治疗组。疗程均为28d。结果治疗第28天两组有效率分别为97.73%和80.95%,治疗组优于对照组,差异有统计学意义(P<0.05);随访4周后复发率分别为27.27%和45.24%,治疗组低于对照组,差异无统计学意义(P>0.05)。结论消风止痒颗粒联合依巴斯汀治疗慢性荨麻疹痊愈率高,复发率低,安全性较好。Objective To observe efficacy and safety of Xiaofengzhiyang granules combined with ebastine in treatment of chronic urticaria. Methods A total of 86 patients with chronic urticaria were divided into two groups, treatment group was treated with Xiaofengzhiyang granules combined with ebastine and control group with ebastine only. Effect was observed on 14th day and 28th day. Relapse rates were recorded in 4 weeks after treatment. Results Efficient rates of treatment group and control group were 97.73% and 80.95% at 28th day, respectively. There was significantly statistical difference between two groups （ P 〈 0.05 ）. Relapse rates in two groups were 27.27% and 45.24% , respectively. There wasn＇ t significantly statistical differ- ence between two groups （P 〉 0.05）. Conclusion Xiaofengzhiyang granules combined with ebastine have high chnical efficacy and safety in treatment of chronic urticaria.

关 键 词：消风止痒颗粒 依巴斯汀 慢性荨麻疹 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]