小剂量干扰素穴位注射联合中药治疗慢性肝炎肝纤维化临床研究  

Clinical Study on Treatment of Hepatic Fibrosis due to Chronic Hepatitis by Combination of Acupoint Injection of Smal Dose of Interferon with Chinese Drugs

作　　者：过建春[1] 陈素莲[1] 李冰如[1] 吴惟一[1] 屠士行[1] 

机构地区：[1]杭州市第六人民医院,浙江310014

出　　处：《中国针灸》2000年第1期9-11,共3页Chinese Acupuncture & Moxibustion

摘　　要：72例慢性乙肝随机分为治疗组、大剂量干扰素组和常规治疗组,治疗2月后,分别对症状、体征、肝功能、乙肝三系、HBVDNA、肝纤维化指标及治疗前后肝组织活检进行观察对照,结果提示本法对慢性肝炎症状体征的改善、恢复肝功能、抗病毒、改善肝纤维化指标及肝组织病理有一定疗效,尤其对抗病毒、血清球蛋白及肝纤维化指标的改善与常规治疗组比较差异有显著性意义(P<001),与大剂量干扰素组比较疗效相似(P>005)。cases of chronic hepatitis B were randomly assigned to treatment group,large dose interferon treatment group and routine treatment group.Control observation on symptoms,signs,hepatic function,HBeAg,HBV DNA,indexes of hepatic fibrosis and biopsy of liver were carried out before and after treatment of 2 months.Results indicated that the therapy has a certain therapeutic effect in improving symptoms and signs of chronic hepatitis,recovering hepatic function,anti virus,improving the indexes of hepatic fibrosis and pathological changes of hepatic tissue,with significant difference( P <0 001)in anti virus and improvement of serum globulin and the indexes of hepatic fibrosis as compared with the routine treatment group,and similar therapeutic effects with the large dose treatment group( P >0 05).

关 键 词：乙型肝炎 中医药疗法 肝纤维化 干扰素Α 

分 类 号：R259.126.2[医药卫生—中西医结合] R259.952[医药卫生—中医内科学]