CAN/PEG-400体系催化合成氧杂蒽二酮类衍生物  

Catalytic Synthesis of Xanthenedione Derivatives by CAN/PEG-400 System

作　　者：曹瑞伟[1] 陈朝辉[1] 吴春雷[2] 周玉波[2] 高晓忠[2] 黄云云[2] 王欢欢[2] 

机构地区：[1]浙江医药股份有限公司新昌制药厂,浙江新昌312500 [2]绍兴文理学院化学化工学院,浙江绍兴312000

出　　处：《合成化学》2012年第4期511-514,共4页Chinese Journal of Synthetic Chemistry

基　　金：国家自然科学基金资助项目(21176156)

摘　　要：以硝酸铈铵(CAN)为催化剂,PEG-400为溶剂,芳香醛与β-环己二酮于85℃反应2.0 h～3.0 h合成了一系列氧杂蒽类衍生物,收率83%～96%,其结构经1H NMR和13C NMR确证。CAN/PEG-400可回收套用4次。A series of xanthenedione derivatives in yield of 83% -96% were synthesized by the reaction of aromatic aldehydes with β- cyclohexanedione using ammonium ceric nitrate（CAN） as the catalyst and PEG-400 as the solvent at 85 ℃ for 2.0 h-3.0 h.The structures were confirmed by 1H NMR and 13C NMR.CAN/PEG-400 can be recycled reuse four times.

关 键 词：β-环己二酮 硝酸铈铵 氧杂蒽 合成 

分 类 号：O626.13[理学—有机化学]