2005—2010年广东省育龄妇女人群中二期梅毒及隐性梅毒流行趋势分析  

Epidemiological trends of the secondary and latent syphilis among women of childbearing age in Guangdong Province of China:from 2005 to 2010

作　　者：任旭琦[1] 杨立刚[1] 陈永锋[1] 刘凤英[1] 洪璇[1] 杨斌[1] 

机构地区：[1]广东省皮肤性病防治中心,广东广州510009

出　　处：《中国感染控制杂志》2012年第3期174-177,共4页Chinese Journal of Infection Control

摘　　要：目的对广东省2005—2010年育龄妇女(15～49岁)人群中二期梅毒及隐性梅毒的流行趋势进行分析。方法对中国疾病监测信息报告管理系统中梅毒疫情报告数据进行统计分析。结果 (1)流行趋势:广东省育龄妇女人群隐性梅毒发病率自2005年的17.37/10万(病例数3 300例)增加至2010年的49.79/10万(病例数10 100例),平均年增长率为24.55%,χ2趋势检验结果显示呈快速递增状态(χ2=4.85,P=0.028);而二期梅毒呈轻度下降,年平均增长率为-2.42%(χ2=3.31,P=0.069)。(2)年龄分布:主要以25～35岁人群发病率较高,达85.45/10万～98.75/10万。(3)疫情上报医疗机构构成比:以综合医院为主,占60.86%;其次为妇幼保健院(14.26%)、皮肤病防治机构(10.32%);卫生院、社区卫生服务中心等基层医疗机构仅占1.66%。结论广东省育龄妇女人群中二期梅毒呈轻度下降,而隐性梅毒则呈快速增长趋势,提示应加大在育龄妇女中的梅毒筛查力度,同时还应进一步加强基层医疗机构的梅毒筛查能力建设,以控制育龄妇女人群中梅毒疫情的上升及母婴梅毒的传播。Objective To analyze the epidemiological trends of the secondary and latent syphilis among women of childbearing age （15 - 49 years old） in Guangdong Province of China from 2005 to 2010. Methods Data collected from China Information System for Diseases Control and Prevention were analyzed statistically. Results （1） Epide- miological trend： The incidence of latent syphilis among women of childbearing age in Guangdong Province of China increased from 17. 37/100 000 （3 300 patients） in 2005 to 49. 79/100 000 （10 100 patients） in 2010, with an aver- age annual increase rate of 24. 55 % （x2 = 4. 85, P = 0. 028） ;the epidemiological trend of secondary syphilis slightly declined with an average annual increase rate of - 2. 42% （x2 = 3. 31, P = 0. 069）. （2） Age distribution： A higher incidence was found among women aged 25 - 35 years old, which was up to 85. 45/100 000 - 98. 75/100 000. （3） Proportions of reports by different medical institutions： General hospitals accounted for 60. 86%, followed by ma- ternal and children health hospitals （14. 26%）, institutes of skin disease prevention （10. 32%）, and primary care institutes including hygiene stations and community health service centers （1.66%）. Conclusion Slightly decreased incidence of secondary syphilis and rapid increase in latent syphilis among women of childbearing ages called for greater efforts in screening syphilis and raised capacity of screening at primary care institutes. Such endeavors will contribute to the control of the increasing incidence of syphilis among those women and mother-to-child transmission of syphilis.

关 键 词：育龄妇女 梅毒 二期梅毒 隐性梅毒 流行趋势 性传播疾病 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]