伊布利特联合电复律转复心房颤动的临床研究  

Clinical research of treating atrial fibrillation by ibutilide combined with electrical cardioversion

作　　者：刘道喜[1] 唐平[1] 王伺伟[1] 葛志艳[1] 

机构地区：[1]江苏省沭阳县人民医院急救中心,江苏沭阳223600

出　　处：《中医临床研究》2012年第13期17-19,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:观察电复律转复心房颤动时联用伊布利特的疗效。方法:按照制定的入选标准及排除标准选择受试者,采用随机单盲对照进行观察。40例房颤患者随机分入两组,单用电复律组(对照组n=20)以100～200J作同步电复律,联用伊布利特组(治疗组n=20)在电复律前缓慢静脉注射1mg伊布利特10min,再行电复律,记录患者每次电除颤能量,电复律后心电监护24h。结果:对照组电转复成功14例(70%),24h早期复发2例;治疗组均一次转复成功(100%),24h心电监护均维持窦律,且治疗组的电除颤能量明显低于对照组[(160±7.5)JVS(210±8.5)J](P<0.01)。结论:伊布利特的药物强化治疗明显提高房颤电转复的成功率,还有利于电转复后窦律的维持。Objective： To observe the clinical effect of atrial fibrillation joint ibutilide cardio version. Methods： 40 consecutive patients （aged 20--75 years） suffering from AF lasting less than 3 months （ranged from 3 hours to 90 days） were randomly assigned into two groups： electro version group （control group, n=20） receiving 100-200J synchronized cardio version and Ibutilide combined with electro version group （treatment group, n=20） receiving intravenous lbutilide lmg over 10 minutes before synchronized cardio version. The cardio version rate and adverse effects within 24 hours were observed. Results： Successful electrical cardioversion of the control group 14 cases （70%）, and 24h of early recurrence in two cases; treatment group once cardio version （100%）, 24h ECG monitoring are to maintain sinus rhythm, the treatment group defibrillation energy was significantly lower than that of control group [（160±7.5）J VS （210±8.5） J ] （P〈0.01）. Conclusion： Ibutilide medicine intensive treatment significantly improved the success rate of atrial fibrillation electrical cardio version, and conducive to electrical cardio version maintenance of sinus rhythm.

关 键 词：心房颤动 伊布利特 电复律 

分 类 号：R547.7[医药卫生—心血管疾病]