地佐辛用于腹腔镜手术苏醒期的疗效观察  

The clinical efficacy of dezocine in the recovery period of laparoscopic surgery

作　　者：金楠[1] 赵年章[1] 朱咏仪[1] 叶少方[1] 靳永强[1] 鄞巧娜[1] 张桂菁[1] 

机构地区：[1]广州医学院第五附属医院麻醉科,广州510700

出　　处：《国际医药卫生导报》2012年第13期1908-1911,共4页International Medicine and Health Guidance News

摘　　要：目的观察地佐辛用于腹腔镜手术苏醒期的临产效果。方法选取90例腹腔镜择期手术患者，ASA分级I～Ⅱ级，将其随机分成对照组（A组）和地佐辛组（B组），每组45例。均采用气管内插管全身麻醉，手术结束前30min，A组常规麻醉管理，B组静脉注射地佐辛0．1mg／kg。分别记录两组患者在停药后自主呼吸恢复时间、苏醒时间、拔管时间、拔管后5min视觉模拟评分（VAS）、躁动评分。结果A、B两组患者自主呼吸恢复时间[（7．5±2．3）min vs．（7．0±3．8）min，P〉0．05]、苏醒时间[（6．8±2．6）min vs．（6．9±3．5）min，P〉0．05]、拔管时间[（7．4±2．7）min vs．（7．4±3．6）min，P〉0．05]均无统计学差异：拔管后5min VAS评分、躁动等不良反应，两组比较差异有统计学意义（P〈0．05）。结论地佐辛在全身麻醉苏醒期可产生良好的镇痛、镇静效果，减少苏醒期的不适，对患者苏醒时间和自主呼吸恢复时间无明显影响，适用于全身麻醉苏醒期镇痛。Objective To observe the clinical efficacy of dezocine in the recovery period of laparoscopic surgery. Methods Ninety ASA I - 11 patients undergoing elective laparoscopic surgery under general anesthesia were randomly divided into control group （ n = 45 ） and dezocine group （ n = 45 ）. Both groups received general anesthesia. 30 minutes before the completion of surgery, the control group received anesthesia management, while dezocine group B received intravenous dezocine of 0.1ml/kg. Time to spontaneous breath recovery, recovery time and extubation time after drug withdrawal were recorded. Five minutes after extubation, visual analogue scale （ VAS ） and level of restlessness were also recorded. Results There were no significant differences between the two groups at time to spontaneous breath recovery [（ 7.5 ± 2.3 ） min vs. （ 7.0 ± 3.8 ） min, P 〉 0.05], recovery time [（ 6.8 ± 2.6 ） min vs. （ 6.9 ± 3.5 ） min, P 〉 0.05] and extubation time [（ 7.4±2.7 ） min vs. （ 7.4 ± 3.6 ） rain, P 〉 0.05]; the pain scores and level of restlessness were significantly lower in dezocine group than in the control group （ P 〈 0.05 ）. Conclusions Dezocine in recovery period of general anesthesia can produce a good analgesic and sedative effect, reduce the recovery period of discomfort in patients. There is significant effect on recovery time and time to spontaneous breath recovery. It is suitable for analgesia i：a the recovery period of general anesthesia

关 键 词：地佐辛 腹腔镜手术 苏醒期 VAS 躁动 

分 类 号：R614[医药卫生—麻醉学]