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机构地区:[1]广东省佛山市顺德区第一人民医院麻醉科,528300
出 处:《内蒙古中医药》2012年第14期82-83,共2页Inner Mongolia Journal of Traditional Chinese Medicine
摘 要:目的:观察骨科手术肢体缺血再灌注后肌钙蛋白I的动态变化,为围术期心肌保护提供临床依据。方法:选择20例下肢骨科手术病人,均于单侧下肢使用止血带,压力80kPa,持续时间不超过90min。分别在扎止血带前(T0),松止血带后10min(T1),30min(T2),1h(T3),3h(T4),6h(T5)等6个时点,采集静脉血2ml,分离血清,检测肌钙蛋白I(cTnI)及心肌酶谱。结果:在各时间段,cTnI的变化具有显著性差异(P<0.01)。cTnI呈现先高后低的特点,在松止血带后10min后开始升高,松止血带后60min,cTnI达到最高值,然后逐渐下降。结论:cTnI的动态变化特点为临床采用适当的干预方法提供了依据。Objective: To observe cinical change of Troponin I in patients poceeding orthopedics Operation using tourniquet. Methods: 20 pa- tients with lower extremity orthopedic surgery were chosed, and lower limb tourniquet pressure 80 kPa, duration time 〈90 rain. Troponin I (cTnI) was detected before relaxing tourniquet (T0), 10min (T1) ,30min(T2), lh (T3), 3h (T4)and 6h(Ts) after relaxing tourniquet. Results: Compared with that at To, cTnI at T1, T2,T3,T4 and T5 increased markedly (P〈0.01), and cTnI at T3 was the highest value. Conclusion: Rea- sonable clinial interference methods was necessary according to change of Troponin I.
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