胸膜活检标本行基因扩增对结核性胸膜炎的诊断价值  

Clinical value of PCR to pleural biopsy specimen in diagnosis of tuberculous pleuritis

作　　者：张玲莉[1] 刘云梅[1] 纪宪 翟守恒[1] 韩通运 周素芬[1] 杜志平[1] 

机构地区：[1]解放军264医院,太原030001

出　　处：《中国防痨杂志》2000年第1期26-27,共2页Chinese Journal of Antituberculosis

摘　　要：目的　评价胸膜活检组织行聚合酶链反应(PCR)对结核性胸膜炎的诊断价值。方法　PCR检测65例胸膜活检组织中结核分枝杆菌DNA,并与胸水检测及胸膜活检组织病检对比。结果　胸膜活检组织PCR阳性率831%,胸水PCR阳性率为631%,胸膜活检组织病检阳性率为60.0%。前者较后两者更敏感。结论　胸膜活检组织PCR检测对结核性胸膜炎有较高的诊断价值。Objective To evaluate the value of PCR to pleural biopsy specimen in the diagnosis of tuberculous pleuritis.Methods PCR technique was used to detect M.tuberculosis DNA in pleural biopsy specimen of 65 cases.The results were compared with that of pleural liquid PCR and pleural pathological examination respectively.Results The positive rate was 83.1%by pleural biopsy specimen PCR,63.1% by pleural liquid PCR and 60.0%by pleural pathological examination respectively.This method was more sensitive than the two others.Conclusion PCR detection of pleural biopsy specimen had greater diagnostic value in tuberculous pleuritis.

关 键 词：胸膜结核 活组织检查 基因扩增 聚合酶链反应 

分 类 号：R521.7[医药卫生—内科学]