541例呼吸道病毒和病毒抗体检测分析  

Determination of Respiratory Virus and Its Clinical Significance in 541 Patients

作　　者：陶国华[1] 郭新荣[1] 吴俊渊[2] 

机构地区：[1]江苏南通市第一人民医院检验科,南通226001 [2]江苏南通市第一人民医院放免中心,南通226001

出　　处：《标记免疫分析与临床》2000年第1期19-21,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：本文应用APAAP方法对 541例患者的流感病毒A(FluA)、流感病毒B(FluB)、副流感病毒 2 (PIV2 )、副流感病毒 1.3(PIV1.3)、腺病毒 3.7(ADV3.7)以及合胞病毒 (RSV)进行了检测 ,用ELISA法检测了 71例患者血清中的抗ADV和RSV抗体。结果显示呼吸道感染组阳性率为4 6 .6 % (2 0 8/44 6 ) ,非感染性疾病组阳性率为 13.7% (13/95)。ADV和RSV抗原与抗体检测的符合率达 92 .9% (6 5/71)。说明APAAP方法检测呼吸道病毒具有灵敏度高和特异性 ,而且操作简捷。Influenza virus A and influenza virus B, parainfluenza virus 2 and 1.3, adenovirus and respiratory syncytial virus were measured by APAAP in 541 patients. At the same time, serum samples were taken, and immunoglobulin M of antibodies against adenovirus and respiratory syncytial virus were measured by ELISA.The results showed that the positive rates were 46.6%(208/446) in respiratory infection group and 13.7%(13/95) in control group, respectively. The conformation rate was 92.9%(65/71) in antigens and antibodies. So APAAP had a higher sensitivity and selectivity, and it had a simple procedure.

关 键 词：呼吸道病毒感染 单克隆抗体 APAAP法 

分 类 号：R446.6[医药卫生—诊断学]