预防接种与急性播散性脑脊髓炎的因果关系研究进展  

Research Progress about Causal Association between Vaccination and Acute Disseminated Encephalomyelitis

作　　者：王亚敏[1] 刘大卫[2] 

机构地区：[1]北京协和医学院公共卫生学院,北京102200 [2]中国疾病预防控制中心免疫规划中心,北京100050

出　　处：《中国疫苗和免疫》2012年第3期261-267,共7页Chinese Journal of Vaccines and Immunization

摘　　要：急性播散性脑脊髓炎(Acute Disseminated Encephalo myelitis,ADEM)是一种急性炎症性脱髓鞘疾病。迄今为止,其病因及发病机制尚不清楚,普遍认为与感染、预防接种等因素有关。近年来,预防接种后发生的ADEM备受关注,ADEM与接种部分疫苗有时间上的关联性,但两者因果关系尚无定论。该文通过检索近些年来国内外发表的有关文献,对ADEM的基本情况及预防接种与ADEM的因果关系研究进展进行综述。Acute disseminated encephalomyelitis （ADEM） is an acute inflammatory demyelinating disease. The etiology and pathogenesis of ADEM is still unclear up to now. It is generally considered that infection and vaccination are influences. In recent years, ADEM occurred after vaccination is paid much attention. Temporal association between parts of vaccines and ADEM were reported, but their causality cannot be confirmed. In this paper, the basic situation of ADEM and the research progress about causal association between vaccination and ADEM is reviewed through searching the papers published in latest years.

关 键 词：急性播散性脑脊髓炎 预防接种 疫苗 因果关系 

分 类 号：R186[医药卫生—流行病学]