聚对氨基苯甲酸/TiO_2-石墨烯修饰玻碳电极同时测定扑热息痛和色氨酸  

Simultaneous Determination of Acetaminophen and Tryptophan Based on TiO_2-graphene/poly(4-aminobenzoic acid) Modified Glassy Carbon Electrode

作　　者：许春萱[1] 郭晓海[1] 孙双霞[1] 刘静[1] 

机构地区：[1]信阳师范学院化学化工学院,河南信阳464000

出　　处：《信阳师范学院学报（自然科学版）》2012年第3期355-359,共5页Journal of Xinyang Normal University(Natural Science Edition)

基　　金：河南省高校科技创新人才基金项目(2010HASTIT025)

摘　　要：采用滴涂法和电聚合法制备聚对氨基苯甲酸/TiO2-石墨烯修饰玻碳电极.用循环伏安法和差分脉冲伏安法研究扑热息痛和色氨酸在修饰电极上的电化学行为,据此建立一种扑热息痛和色氨酸同时测定的电化学方法.实验结果表明,该修饰电极对于扑热息痛和色氨酸的电化学反应具有良好的催化性能.利用差分脉冲伏安法测定,扑热息痛和色氨酸在1.0～530μmol/L浓度范围内与氧化峰电流呈良好的线性关系,相关系数分别为0.990和0.993.信噪比为3时,扑热息痛和色氨酸检出限分别为0.4μmol/L和0.1μmol/L.将该方法用于实际样品分析,回收率为95.2%～105.8%.TiO2-graphene （TiO2-Gr） was coated on glassy carbon electrode （GCE） and 4-aminobenzoic acid was then electropolymerized on the modified electrode to fabricated electrochemical sensor. The electrochemical behaviors of aeetaminophen and tryptophan on the modified electrode were investigated by cyclic vohammetry and differential pulse vohammetry. A novel electrochemical method for simultaneous determination of aeetaminophen and tryptophan was developed. The results showed that the modified electrode has good eleetroeatalytic performance toward the electrochemical reaction of acetaminophen and tryptophan. Differential pulse vohammetry was used for the determination of acetaminophen and tryptophan. The concentration of acetaminophen and tryptophan showed good linear relationships with the oxidation peak current in the range of 1.0 - 530 μ mol/L, with correlation coefficients of 0. 990 and 0. 993, respectively. The limits of detection were 0.4 μmol/L and 0.1 μmoL/L （Rsn = 3 ） , respectively. The developed method was used to determine real samples with recoveries of 95.2% - 105.8%.

关 键 词：TiO2-石墨烯 对氨基苯甲酸 扑热息痛 色氨酸 电化学传感器 

分 类 号：O657.15[理学—分析化学]