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机构地区:[1]新乡医学院第三附属医院妇产科,河南新乡453003
出 处:《中国内镜杂志》2012年第7期713-716,共4页China Journal of Endoscopy
摘 要:目的探讨腹腔镜手术治疗早期老年子宫内膜癌的远期疗效。方法选择2004年1月~2009年1月该院妇科收治的早期老年子宫内膜癌患者共60例,按照手术方式将患者分为两组,传统手术组(26例)与腹腔镜手术组(34例)。对两组患者均进行随访,比较2种手术方法的术后远期疗效。结果随访期间,腹腔镜组患者局部复发3例(8.82%),远处转移4例(11.76%);开腹组患者局部复发2例(7.69%),远处转移3例(11.54%)。腹腔镜组的局部复发率和远处转移率均与开腹组差异无显著性(P>0.05)。腹腔镜组和开腹组3年累积总生存率分别为88.2%(30/34)和88.5%(23/26);5年累积总生存率分别为79.4%(27/34)和76.9%(20/26)。腹腔镜组和开腹组3年无瘤生存率分别为82.4%(28/34)和80.8%(21/26);5年无瘤生存率分别为70.6%(24/34)和73.1%(19/26)。两组总生存率曲线和无瘤生存率曲线相比差异均无显著性(P>0.05)。结论腹腔镜手术可取得与传统开腹手术相同的远期疗效,是治疗早期老年子宫内膜癌患者的一个很好的选择。[ Objective ] To investigate the long-term curative effects of laparoscopic surgery for patients with stage I and II endometrial cancer in the old. [ Methods ] Sixty patients with stage I and II endometrial cancer in the old from Jan. 2004 to Jan. 2009 were divided into 2 groups according to receiving laparoscopic hysterectomy or not: laparoscopic surgery group (34 cases) and open laparotomy group (26 cases). The survival time during long-term fol- low-up between the two groups was compared. [ Results ] The incidence of recurrence and distant metastasis were respectively 8.82%, 11.76% and 7.69%, 11.54% in laparoscopic surgery group and open laparotomy group. No sig- nificant differences were found in the incidence of recmxence and distant metastasis between open and laparoscopy groups (P 〉0.05). The total survival rates in 3 years were respectively 88.2%(30/34) and 88.5% (23/26) in laparo- scopie surgery group and open laparotomy group. The total survival rates in 5 years were respectively 79.4%(27/34) and 76.9%(20/26)in laparoscopic surgery group and open laparotomy group. The disease-free survival rates in 3 years were respectively 82.4%(28/34) and 80.8%(21/26) in laparoscopic surgery group and open laparotomy group. The disease-free survival rates in 5 years were respectively 70.6% (24/34) and 73.1% (19/26) in laparoscopic surgery group and open laparotomy group. No significant differences were found in the survival rate and disease-free survival between open and laparoscopy groups (P 〉0.05). [ Conclusion ] Laparoscopic surgery can achieve the same long-term curative effect as open laparotomy for patients with stage I and II endometrial cancer in old, serves as a better treatment for patients.
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