慢性假性肠梗阻的临床特征  

Study on clinical manifestations of chronic intestinal pseudo-obstruction in 11 cases

作　　者：孟凡冬[1] 吴咏冬[1] 李文燕[1] 王拥军[1] 赵海英[1] 

机构地区：[1]首都医科大学附属北京友谊医院消化内科,北京100050

出　　处：《临床和实验医学杂志》2012年第16期1266-1268,共3页Journal of Clinical and Experimental Medicine

摘　　要：目的分析慢性假性肠梗阻(CIPO)患者的临床及实验室特点,以提高临床医生对本病的认识。方法回顾性分析我院1998～2010年间诊断的11例CIPO。对患者临床特点、实验室检查、治疗及预后等方面进行总结。结果患者的主要临床表现为反复发作的腹痛、腹胀和恶心、呕吐,部分患者有间断腹泻或腹泻与便秘交替;影像学检查提示肠梗阻;相关检查未发现机械性肠梗阻的依据;均符合CIPO的诊断标准。11例患者中,原发性小肠内脏肌病4例,另外7例中,6例继发于系统性红斑狼疮,1例继发于系统性硬化症。结论 CIPO是一种少见的严重疾病,长期预后较差。多数患者可能经历严重的并发症,其中部分与治疗有关。由于缺乏特异性的诊断标准,且本病常与其他原发病重叠,因此诊断困难。对于本病认识的提高和早期诊断有助于提高疗效、改善患者的生活质量。Objectives To explore the clinical features of chronic intestinal pseudo - obstruction （CIPO）. Methods The clinical data of eleven patients with CIPO admitted in this hospital during 1998 to 2010 were retrospectively analyzed. The clinical characteristics, serological findings, treatment and prognosis of these patients were summarized. Results All these 11 patients met with the CIPO diagnostic criteria; they were： a） episode of intestinal subocclusion; b） evidence of a dilated small bowel; and c） exclusion of mechanical cause of intestinal obstruction. Four of them were diagnosed as primary CIPO and other seven cases were secondary to systemic diseases including six of them with systemic lupus erythematosus and one with systemic sclerosis. Conclusion CIPO is a rare, severe and potentially life - threatening functional digestive disorder. Majority of patients may experience disability and potentially life - threatening complications over time. Diagnosis and management of CIPO remain extremely challenging. A greater awareness of its clinical features by physicians would help to recognize possible underlying causes and limit surgi- cal procedure to a minimum.

关 键 词：慢性假性肠梗阻 临床特征 系统性红斑狼疮 系统性硬化症 

分 类 号：R656.7[医药卫生—外科学]