MEF2基因家族的研究进展  

The Research Progress of MEF2 Gene Family

作　　者：程波[1] 李利[1] 王林杰[1] 张红平[1] 

机构地区：[1]四川农业大学动物遗传育种研究所,四川雅安625014

出　　处：《中国畜牧杂志》2012年第15期70-74,共5页Chinese Journal of Animal Science

基　　金：四川省科技支撑计划(2011NZ0003;2011NZ0017)

摘　　要：肌细胞增强因子2(MEF2)属于转录调节因子MADS-Box家族,是一种特定的转录因子。在脊椎动物中,MEF2基因家族由4个基因组成,包括MEF2A、MEF2B、MEF2C和MEF2D,它们在肌肉生成、神经系统发育和分化、肝纤维化方面均有重要作用。本文从MEF2基因的结构、组织分布和生物学功能等方面,对该基因家族的研究进展进行了综述。Myocyte enhancer factor 2 （MEF2） is a specific transcription factor of MADS-Box family. It is a single gene in Drosophila and C. Elegans, but in vertebrates, MEF2 gene are multi-gene family, including MEF2A, MEF2B, MEF2C and MEF2D. They took an important role in myogenesis, development and differentiation of nervous system and liver fibrosis.The structure, tissue distribution and biological function of MEF2 genes were summarized in this review paper.

关 键 词：肌细胞增强因子2 生物学功能 综述 

分 类 号：S813.1[农业科学—畜牧学]