重组牛碱性成纤维细胞生长因子在老年糖尿病足患者溃疡中的应用及护理  

Application and nursing of recombinant bovine basic fibroblast growth factor in senile patients withdiabetic foot ulcer

作　　者：陈冬梅[1] 郑冬杏[1] 黄健宁[1] 苏海丹[1] 

机构地区：[1]广东医学院附属医院,湛江524001

出　　处：《中国实用护理杂志》2012年第22期28-30,共3页Chinese Journal of Practical Nursing

摘　　要：目的探讨重组牛碱性成纤维细胞生长因子（rbbFGF）对老年糖尿病足溃疡的疗效，总结护理方法。方法将28例老年糖尿病足溃疡患者分为治疗组和对照组各14例，对照组采用内科治疗加局部换药治疗，治疗组采用内科治疗加局部换药并外涂rbbFGF进行治疗，比较2组在肉芽组织成熟度、创面愈合时间和疗效方面的差异，并对护理方法进行总结。结果治疗组在第9、13天创面肉芽组织成熟度优于对照组；在第14、21和28天创面愈合速度优于对照组；治疗组创面愈合时间为（29．87±5．73）d，对照组为（38．49±6．58）d，2组比较差异显著；治疗4周后治疗组疗效显著优于对照组。结论rbbFGF对老年糖尿病足溃疡具有良好的治疗效果；恰当的护理方法有助于患者的康复。Objeclive To investigate the curative effect of recombinant bovine basic fibroblast growth fac- tor （rbbFGF）in the treatment of senile diabetic foot ulcer and summarize the nursing methods. Methods 28 elderly patients with senile diabetic foot ulcer were divided into the control group and the treatment group with 14 patients in each group. The control group was given medical treatment and local wound dressing change, the treatment group was given rbbFGF based upon the above method. The degree of granulation tissue maturity, wound healing time and therapeutic effects were compared between these two groups. The nursing measures were summarized. Results On the 9th day and 13th day, granulation tissue maturity degree of the treatment group was better than the control group. On the 14th day, 21th day and 28th day, endepidermis growth velocity of the treatment group was better than the control group. The wound healing time of the treatment group was （29.87~5.73） d and was significantly shorter than （38.49~6.58） d of the control group. The therapeutic effect of the treatment group was better than that of control group on the 28th day. Conclusions Application of rbbFGF has good curative effect on senile diabetic foot ulcer and suit- able nursing care methods contributes to recovery of elderly patients.

关 键 词：重组牛碱性成纤维细胞生长因子 糖尿病足 护理 

分 类 号：R473.6[医药卫生—护理学]