全血细胞计数移动均值法质量控制规则应用的探讨  

Exploration the application of quality control rules for complete blood count moving average method

作　　者：唐继海[1] 李炎鑫[1] 黄文方[1] 税含[1] 王太芬[1] 王川蓉[1] 

机构地区：[1]四川省医学科学院/四川省人民医院检验科,成都610071

出　　处：《检验医学与临床》2012年第14期1684-1686,共3页Laboratory Medicine and Clinic

摘　　要：目的通过12S(警告限),13S规则和X-B质控方法联合应用于全血细胞计数检测室内质量控制,来寻求临床实验室全血细胞计数不同参数室内质控的质控方法的适用者。方法迈瑞全自动血液分析仪BC-5500上所做的原装高、中、低三个水平质控品的质控数据,用12S(警告限),13S规则和仪器自带的X-B功能同时对红细胞平均体积(MCV)、红细胞平均血红蛋白量(MCH)和平均红细胞血红蛋白浓度(MCHC)进行质控分析。结果 X-B质控图上全部质控结果在控,而L-J规则进行判断的质控图上随着时间的延长部分参数MCV、血细胞比容(HCT)、MCHC开始出现假性失控。结论全血细胞计数质控品部分参数MCV、HCT、MCHC稳定性受限于开瓶时间的限制,临床实验室全血细胞计数室内质控不适宜用L-J质控规则进行判断,而更适合用X-B进行判断。Objective To estimate the internal quality control results of whole blood cells count by using 12S（warning limit）,13S rule and X-B quality control rule separately,and find out which one is more suitable for clinical labs.Methods We used automatic Mindray BC-5500 Hematology Analyzer to detect the original high,normal and low level of quality control materials for quality control data.According to the 12S（warning limit）,13S rules and X-B quality control rules,we analyzed MCV,MCH,MCHC quality control data.Results All the results in the X-B quality control chart were under control,and L-J rules to determine the quality control chart with time extension on some parameters as MCV,HCT,MCHC showed false rejection.Conclusion Some parameters as MCV,HCT,MCHC of blood cell count materials are limited by the time constraints of opening bottles.The internal quality control of complete blood count in clinical laboratory judged by L-J rule is not suitable,but suitable by X-B rule.

关 键 词：室内质控 全血细胞计数 L-J质控 X-B质控 控制限 

分 类 号：R446.113[医药卫生—诊断学]