Tei指数对评价妊娠中晚期胎儿孤立性心包积液左心功能的价值  

Value of Tei index in Evaluation of Left Ventricular Function in Second-third Trimester Fetuses with Isolated Pericardial Effusion

作　　者：胡智安[1] 韩鄂辉[1] 张频[1] 朱静安[1] 吕志红[1] 洪玮[1] 王从农[1] 喻磊[1] 黄娅娟[1] 刘锦萍[1] 

机构地区：[1]黄石市中心医院功能科,湖北黄石435000

出　　处：《南昌大学学报（医学版）》2012年第6期43-47,共5页Journal of Nanchang University：Medical Sciences

摘　　要：目的测量妊娠中晚期胎儿孤立性心包积液左心室的Tei指数,分析Tei指数与胎龄的关系,初步评估其临床应用价值。方法选择产前经彩色多普勒超声检查显示有心包积液、没有结构异常及心律异常胎儿的孕妇(异常组)53例,其胎儿均为孤立性心包积液[胎儿53例,男28例,女25例,胎龄18～23(20.3±0.4)周]。分别于<23、≥23～<27、≥27～<31、≥31～<35、≥35孕周进行胎儿超声心动图检查,同时应用组织多普勒技术测量左心室的Tei指数,并与正常对照组进行比较。结果心包积液大量组<23孕周ICT+IRT、Tei指数值均明显高于正常对照组(均P<0.05),中量组<23、≥31～<35孕周ICT+IRT值均明显低于大量组(均P<0.05),大量组、中量组≥23～<27、≥27～<31、≥31～<35、≥35孕周ICT+IRT值明显高于正常对照组、少量组(均P<0.05),中量组≥23～<27、≥27～<31孕周ICT+IRT、Tei指数值均明显低于大量组(均P<0.05),大量组≥23～<27、≥27～<31、≥31～<35、≥35孕周的Tei指数值均明显高于正常对照组、少量组(均P<0.05),中量组≥27～<31、≥35孕周Tei指数值均明显高于正常对照组、少量组(均P<0.05)。结论妊娠中晚期胎儿孤立性心包积液有少量的,其左心室的整体功能正常;胎儿孤立性心包积液有中量及大量的,其左心室的整体功能减低。Tei指数测量方法简单、快捷、可靠,Tei指数是评价妊娠期心包积液胎儿心功能和预后的理想指标。Objective To measure left ventricular Tei index in second-third trimester fetuses with isolated pericardial effusion to investigate its relationship with gestational age,and to make a preliminary assessment of its clinical value.Methods Fifty-three second-third trimester fetuses without cardiac structural and rhythm abnormalities [28 male and 25 female;gestational age,18-23（20.3±0.4）week] were examined by fetal echocardiography because of isolated fetal pericardial effusion confirmed by color doppler ultrasound.Fetal echocardiography was performed and left ventricular Tei index was measured with tissue doppler imaging technique at less than 〈23,≥23-〈27,≥27-〈31,≥31-〈35 and more than ≥35 weeks of gestation,respectively.The results were compared with normal controls.Results The sum of isovolumic contraction and relaxation time（ICT＋IRT values） and Tei index in large pericardial effusion group were significantly greater than those in control group at less than 〈23 weeks of gestation（all P〈0.05）.The ICT＋IRT values in middle pericardial effusion group were significantly less than those in large pericardial effusion group at less than ≥23-〈31 and ≥31-≥35 weeks of gestation（all P〈0.05）.The ICT＋IRT values in moderate and large pericardial effusion groups were significantly greater than those in control group and small pericardial effusion group at ≥23-〈27,≥27-〈31,≥31-〈35 and more than ≥35 weeks of gestation（all P〈0.05）.The ICT＋IRT values and Tei index in moderate pericardial effusion group were significantly less than those in large pericardial effusion group at ≥23-〈27 and ≥27-〈31 weeks of gestation（all P〈0.05）.Tei index in large pericardial effusion group was obviously greater than that in control group and small pericardial effusion group at ≥23-〈27,≥27-〈31,≥31-〈35 and more than ≥35 weeks of gestation（all P〈0.05）.Tei index in moderate pericardial effusion group was obviously greater than that in control group and

关 键 词：孤立性心包积液 超声心动图 心脏 TEI指数 心功能 胎龄 胎儿 

分 类 号：R445.1[医药卫生—影像医学与核医学] R542.1[医药卫生—诊断学]