辛伐他汀与非诺贝特合用致横纹肌溶解症1例  

Rhabdomyolysis Related to Simvastatin-fenofibrate Combinations

作　　者：胡晓蕾[1] 王渝[1] 何菊英[1] 

机构地区：[1]第三军医大学第一附属医院药剂科,重庆400038

出　　处：《药品评价》2012年第11期34-35,共2页Drug Evaluation

摘　　要：1例76岁女性糖尿病患者,因高血脂联合使用辛伐他汀(40mg/晚)和非诺贝特(200mg/早),出现双侧腓肠肌压痛,CK值为10268 IU/L。停用两种降脂药后,给予补液和改善微循环等对症治疗,症状逐渐好转。One 76-year-old female diabetes patient took simvastatin （40mg, qn） and fenofibrate （200mg, qd） orally and simultaneously. The patient experienced pressing pain on bilateral calf muscle and her CK was 10268 IU/L. The patient＇s symptoms have alleviated after giving up both of the two drugs, and instead giving fluid infusion and promoted microcirculation treatments.

关 键 词：辛伐他汀 非诺贝特 横纹肌溶解症 不良反应 

分 类 号：R595.3[医药卫生—内科学]