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作 者:陈再玲[1]
机构地区:[1]湖南株洲市三医院药剂科,湖南株洲412003
出 处:《中国医院用药评价与分析》2012年第6期516-518,共3页Evaluation and Analysis of Drug-use in Hospitals of China
摘 要:目的:了解门诊和住院患者麻醉药品和一类精神药品使用情况,为临床合理使用该类药品提供依据。方法:调查2011年1—12月门诊和住院患者麻醉药品和一类精神药品处方8 411张,采用世界卫生组织(WHO)推荐的限定日剂量(DDD)和药物利用指数(DUI)进行统计、分析。结果:用药频度(DDDs)最大的为注射用盐酸瑞芬太尼,其次为枸橼酸芬太尼注射液,主要用于手术镇痛;用于癌性疼痛治疗的药物以硫酸吗啡缓释片的DDDs为最大。注射用盐酸瑞芬太尼和枸橼酸芬太尼注射液DUI近似于1.0,其他药物的DUI均<1.0。结论:癌性疼痛第三阶梯用药主要以口服吗啡为主,符合WHO的要求;麻醉药品和一类精神药品的使用基本合理。OBJECTIVE : To investigate the use of narcotic drugs and the first category of psychotropic drugs in our hospital (including outpatients and inpatients) so as to provide reference for clinical rational drug use. METHODS: A total of 8 411 prescriptions of narcotic drugs and the first category of psychotropic drugs for the inpatients and outpatients of our hospital from Jan. 2011 to Dec. 2011 were collected and statistically analyzed with regard to defined daily dose (DDD) and drug utilization index (DUI) recommended by WHO. RESULTS: In terms of DDDs, Remifentanil Hydroehloride for Injection took the lead followed by Fentanyl Citrate Injection, which were mainly used for pain-relieving during operation. With respect to cancer pain management, morphine sulfate sustained-release tablet took the lead in terms of DDDs. The DUI of Remifentanil Hydrochloride for Injection and Fentanyl Citrate Injection were approximately 1.0, and the DUI for the other drugs were less than 1.0. CONCLUSION: Oral morphine was the predominant drug for the third hierarchy cancer pain management, which is up to the standard of WHO. The utilization of narcotic drugs and the first category of psychotropic drugs were basically rational in our hospital.
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