Effects of fluid recirculation on mass transfer from the arterial surface to flowing blood  

作　　者：Zhi-Guo Zhang Xi-Wen Zhang Ying-Xi Liu 

机构地区：[1]Department of Engineering Mechanics,Faculty of Vehicle Engineering and Mechanics,State Key Laboratory of Structural Analysisfor Industrial Equipment,Dalian University of Technology,116024 Dalian,China [2]School of Aerospace,Tsinghua University,100084 Beijing,China

出　　处：《Acta Mechanica Sinica》2012年第3期904-910,共7页力学学报（英文版）

基　　金：supported by the National Natural Science Foundation of China (10672090,11002034,11072055 and 11032008);the National High Technology Research and Development Program of China (2006AA02Z4E8);the China Postdoctoral Science Foundation

摘　　要：The effect of disturbed flow on the mass trans- fer from arterial surface to flowing blood was studied nu- merically, and the results were compared with that of our previous work. The arterial wall was assumed to be vis- coelastic and the blood was assumed to be incompressible and non-Newtonian fluid, which is more close to human arte- rial system. Numerical results indicated that the mass trans- fer from the arterial surface to flowing blood in regions of disturbed flow is positively related with the wall shear rates and it is significantly enhanced in regions of disturbed flow with a local minimum around the reattachment point which is higher than the average value of the downstream. There- fore, it may be implied that the accumulation of cholesterol or lipids within atheromatous plaques is not caused by the reduced efflux of cholesterol or lipids, but by the infiltration of the LDL （low-density lipoprotein） from the flowing blood to the arterial wall.The effect of disturbed flow on the mass trans- fer from arterial surface to flowing blood was studied nu- merically, and the results were compared with that of our previous work. The arterial wall was assumed to be vis- coelastic and the blood was assumed to be incompressible and non-Newtonian fluid, which is more close to human arte- rial system. Numerical results indicated that the mass trans- fer from the arterial surface to flowing blood in regions of disturbed flow is positively related with the wall shear rates and it is significantly enhanced in regions of disturbed flow with a local minimum around the reattachment point which is higher than the average value of the downstream. There- fore, it may be implied that the accumulation of cholesterol or lipids within atheromatous plaques is not caused by the reduced efflux of cholesterol or lipids, but by the infiltration of the LDL （low-density lipoprotein） from the flowing blood to the arterial wall.

关 键 词：Disturbed flow Arterial wall Mass transfer Atherosclerosis Wall shear rates 

分 类 号：O373[理学—流体力学] TQ051.65[理学—力学]