儿童不典型黄癣1例报告及文献复习  

Atypical favus in child:a case report and literature review

作　　者：李莉 郑冬燕[2] 王韵茹[1] 朱均昊[1] 章强强[1] 

机构地区：[1]复旦大学附属华山医院皮肤科真菌室,上海200040 [2]广西医科大学一附院皮肤科,南宁530021

出　　处：《中国真菌学杂志》2012年第2期101-103,共3页Chinese Journal of Mycology

摘　　要：报告1例由许兰毛癣菌(Trichophyton schoenleinii)引起的儿童不典型黄癣,患儿临床症状轻微,缺乏蜡黄色、碟形黄癣痂和特殊的鼠臭味等典型临床症状。病发真菌直接镜检见大量不规则菌丝,间生膨大,大小不等、形态不规则的孢子,真菌培养为许兰毛癣菌生长,经分子生物学测序鉴定证实。E-test药敏结果显示伊曲康唑、两性霉素B、卡泊芬净及伏立康唑均敏感。经口服伊曲康唑胶囊及外用2%舍他康唑乳膏治疗基本痊愈。A case report of atypical favus in child caused by Trichophyton schoenleinii. With mild clinical symptoms, the child lacked some typical clinical signs as： concave disc formed sulfur-yellow crusts, characteristics of the rat smell, et al. Direct microscopic examination of the infected hairs found a large number of irregular hyphae, intercalary swollen spores with unequal size and irregular shape Trichophyton schoenleinii was growth on fungal culture media and confirmed by DNA sequencing. Drug susceptibility （E-test） results showed the isolated strain was sensitive to itraconazole, amphotericin-B, caspofungin and voriconazole. The lesions were recovered in two months by oral itraconazole capsule and topical 2% sertaconazole cream.

关 键 词：黄癣 许兰毛癣菌 舍他康唑 

分 类 号：R756.1[医药卫生—皮肤病学与性病学]