男性高血压患者动态血压节律异常与良性前列腺增生的相关性研究  

Research on correlation between abnormal circadian rhythm of ambulatory blood pressure monitoring and benign prostatic hyperplasia in male patients with essential hypertension

作　　者：马金宝[1] 秦明照[1] 

机构地区：[1]首都医科大学附属北京同仁医院干部医疗科,北京100730

出　　处：《东南大学学报（医学版）》2012年第4期453-455,共3页Journal of Southeast University(Medical Science Edition)

摘　　要：目的:探讨男性高血压患者血压节律异常与良性前列腺增生间的相关性。方法:对198例(45～92岁)高血压合并良性前列性增生的患者进行24 h动态血压监测,根据夜间血压下降率分为杓型组(100例)和非杓型组(98例),比较两组患者低密度脂蛋白、糖化血红蛋白、踝臂指数、收缩压、舒张压、前列腺抗原及前列腺体积。结果:非杓型组和杓型组昼间收缩压[(130.2±9.4)mmHg vs(128.6±7.5)mmHg,(1 mmHg=0.133 kPa)]、昼间舒张压[(76.0±6.1)mmHg vs(75.8±5.5)mmHg]无明显差异,但夜间收缩压[(134.8±9.7)mmHg vs(115.6±3.0)mmHg]及夜间舒张压[(78.8±6.5)mmHg vs(67.5±2.7)mmHg]有显著性差异(P<0.05),非杓型组和杓型组患者前列腺体积有显著性差异[(44.8±11.6)ml vs(35.4±9.9)ml,P<0.05]。结论:血压患者血压节律异常与前列腺增生程度可能存在相关性。Objective： To investigate the correlation between the circadian rhythm abnormality of blood pressure and benign prostatic hyperplasia in male patients with essential hypertension. Methods： One hundred and ninety-eight male hypertensive patients（aged 45 to 92 years） were included and divided into dipper group （100 patients） and non- dipper group （98 patients ） according to the rate of decrease in nocturnal blood pressure by ambulatory blood pressure monitoring. LDL-C, GHb, ABI, SBP, DBP, prostatic antigen and prostatic volume were recorded. Results： There were no statistical differences between non-dipper group and dipper group in day systolic blood pressure [ （ 130. 2±9. 4） mmHg vs （ 128.6±7.5 ） mmHg ] and day diastolic blood pressure [ （76. 0±6. 1 ） mmHg vs （75.8±5.5） mmHg] （P 〉0. 05）. Night systolic blood pressure [ （134. 8 ±9. 7） mmHg vs（ 115.6±3.0） mmHg] and night diastolic blood pressure [ （78.8±6.5 ） mmHg vs （67.5± 2.7 ） mmHg ] in non- dipper group were significantly higher than those in dipper group（P 〈 0.05 ）. Prostatic volume in non-dipper group were significantly higher than those in dipper group [ （44. 8±11.6） ml vs（35.4 ±9.9） ml]. Conclusions： The circadian rhythm abnormality of blood pressure in patients with essential hypertension may be associated with the degree of prostatic hyperplasia.

关 键 词：高血压 动态血压监测 昼夜节律 良性前列腺增生 

分 类 号：R544.1[医药卫生—心血管疾病] R697.32[医药卫生—内科学]