某院280例药物不良反应分析  

Analysis of 280 Cases of Adverse Drug Reactions in A Hospital

作　　者：余靖华[1] 潘志强[1] 邓冲[1] 

机构地区：[1]南方医科大学附属南海医院,广东佛山528000

出　　处：《今日药学》2012年第6期359-360,364,共3页Pharmacy Today

摘　　要：目的对本院呈报给国家ADR中心的280例药物不良反应(ADR)监测报告进行分析。方法收集2009-12～2010-12南海人民医院呈报给国家ADR中心的280例药物不良反应报告,对其进行综合分析。结果 ADR的发生率女性比男性高;老年人较容易发生药物不良反应;药物类型中抗生素所占比例最大(48.21%);用药途径中静脉滴注所占比例最大(71.79%);ADR发生部位中皮肤系统最多(58.93%),其次是中枢神经系统(13.21%)。结论应提高临床用药的安全性和合理性,加强药品不良反应的预防和监控。Objective To analyze the adverse drug reaction （ADR） reports in the hospital. Methods A total of 280 cases of adverse drug reactions in our hospital in 2009 - 12 -2010 - 12 that were reported to tile national ADR center were collected and analyzed. Results The incidence of ADR was higher in women than men; the elderly were more prone to occur ADR; antibiotics took the largest proportion （48. 21% ）; intravenous infusion l：ook the largest proportion （71.79%）; ADR occurred most in skin system （58. 93%）, followed by central nervous system （13. 21%）. Conclusion The clinical medication safety and rationality should be improved, and ADR report and monitoring should be strengthened.

关 键 词：药物不良反应(ADR) 监测 

分 类 号：R969[医药卫生—药理学]