3,6-二(3,6-二叔丁基咔唑基)-咔唑的合成研究  

Study on synthesis of 3,6-di(tert-butylcarbazolyl)carbazole

作　　者：孙婷婷[1] 黄斌[1] 周素文[1] 张宏斌[1] 戴念维[1] 丁木生[1] 蒋立建[2] 

机构地区：[1]东南大学成贤学院化工与制药工程系,江苏南京210088 [2]东南大学化学化工学院,江苏南京210088

出　　处：《精细与专用化学品》2012年第7期37-39,共3页Fine and Specialty Chemicals

基　　金：2011年江苏省高等学校大学生实践创新训练计划立项项目(1101300086)

摘　　要：以咔唑为主要原料,经烃化、碘代、磺酰化、Ullmann反应和水解反应合成了3,6-二(3,6-二叔丁基咔唑基)-咔唑,五步反应总收率为50.3%,中间体及产品进行了1 HNMR检测。该合成工艺具有路线简单、操作方便、产率高等优点,适合大批量制备。3,6-Di（tert-butylcarbazolyl）carbazole was synthesized by using carbazole as the starting material via alkylation, iodination, sulfonylation, Ullmann reaction and hydrolysis reaction. The total yield of five steps was 50.3%. Structure of the product and intermediate was confirmed by i HNMR and MS. This method has many advantages, such as easy operation and high yield, which can he feasible to large scale preparation.

关 键 词：咔唑 ULLMANN反应 3 6-二-(3 6-二叔丁基咔唑基)-咔唑 

分 类 号：TQ252[化学工程—有机化工]