无症状肝功酶学指标异常的系统观察及在健康状况评估中的价值  

Health assessment in basis of enzyme indexes in serum

作　　者：任飒爽[1] 刘颖[2] 马悦[3] 刘辉[1] 

机构地区：[1]大连医科大学检验医学院,辽宁省大连市116044 [2]大连医科大学附属第二医院体检中心,116044 [3]大连医科大学附属第二医院检验科,116044

出　　处：《实用医学杂志》2012年第14期2443-2445,共3页The Journal of Practical Medicine

基　　金：国家自然科学基金(编号:30770724)

摘　　要：目的:探讨亚健康体检人群肝功酶学指标的变化与轻度器质性病变的关系。方法:选取无明显各类疾病症状的健康体检者345名,体检项目包括:腹部超声检查,X光片及CT的检查,肝功酶学指标(ALT、AST、GGT)。将健康体检者按三种酶异常情况分为4组:任意一种酶浓度异常组、任意两种酶浓度异常组、三种酶浓度均异常组、三种酶浓度均在参考值范围内组。结果:上述4组的超声、X片、CT异常的平均项目数分别为1.10;1.73;1.73;1.86,可见随着酶异常项目的增多,体检超声、X片、CT异常项目数也增多。结论:酶异常与体检异常项目数有着非常密切的关联,无主观自觉症状的健康体检人群的肝功酶学指标异常可能与影像学检出之前的脏器轻度损伤有关联。Objective To explore the relationship between mild organic damage and the change of liver function enzyme indexes and set up the method for health assessment by enzyme indexes in serum.Methods The 345 subjects were recruited without any disease symptoms.Examinations involved abdomen ultrasound pattern,chest X-ray,and liver functions which including serum biochemical indexes level of ALT,AST,GGT.The study population was divided into four groups by enzyme abnormalities.Result Comparing the average of the abnormal item in the image detection,the numbers of image detection abnormal item are increased with the increasing of enzyme abnormality.Conclusion The abnormality of enzyme indexes relates to mild organic damage.The method for health assessment with enzyme indexes is reasonable in the early stage before image detection of viscera mild damage.

关 键 词：丙氨酸转氨酶 AST GGT 

分 类 号：R446.1[医药卫生—诊断学]