嗜酸粒细胞性胸腔积液相关病因最新研究进展  

Research progress on aetiology of eosinophilic pleural effusion

作　　者：王森森[1] 周敏[2] 

机构地区：[1]上海交通大学附属瑞金临床医学院,200025 [2]上海交通大学附属瑞金医院呼吸科,200025

出　　处：《国际呼吸杂志》2012年第14期1080-1083,共4页International Journal of Respiration

摘　　要：许多病因均可导致嗜酸粒细胞性胸腔积液（EPE）的发生，如感染性疾病、肿瘤、医源性、药物性等。既往认为EPE提示肿瘤低风险，但新近研究表明EPE中肿瘤发生率较非EPE无明显差异，但高比例嗜酸粒细胞可能预示肿瘤发生率低。过去认为结核相关EPE发生率低，但在结核高发地区，结核性胸膜炎伴EPE患者并不少见。气体和（或）血液进入被认为是导致EPE的常见原因，但反复胸穿是否导致EPE高发，报道结果存在争议，需要进一步深入研究。特发性EPE中许多病因需要进一步深入探究。Eosinophilic pleural effusion （EPE） can be caused by various aetiologies, such as infections, tumors, drugs, etc. In most classical articles, EPE indicates a lower risk of malignancy. Recent publications show that the incidence of malignancy shows no obvious difference between EPE and non-EPE,but a high percentage of eosinophils might imply a lower risk of malignancy. The incidence of tuberculosis-related EPE is previously regarded as fairly low, hut in high-risk areas of tuberculosis,it is actually common that EPE in patients with tuberculous pleurisy. Further studies are highly needed due to the present controversy over whether repeated thoracentesis could increase the EPE incidence, as well as to dig out the probable causes of idiopathic EPE.

关 键 词：嗜酸粒细胞 胸腔积液 嗜酸粒细胞性胸腔积液 病因 

分 类 号：R561[医药卫生—呼吸系统]