纳米镍修饰TiO_2纳米管电极检测胰岛素  

Detection of Insulin by Nickel Nanoparticles Modified Titanium Oxide Nanotube Electrode

作　　者：张云怀[1] 董西哲[1] 肖鹏[2] 何辉超[1] 李小玲[1] 

机构地区：[1]重庆大学化工学院,重庆400030 [2]重庆大学物理学院,重庆400030

出　　处：《应用化学》2012年第8期948-953,共6页Chinese Journal of Applied Chemistry

摘　　要：采用阳极氧化法制备出高度有序的TiO2纳米管阵列作为基础电极,通过电沉积法将纳米镍颗粒负载在基础电极上,从而制备了纳米镍-二氧化钛纳米管(Ni/TiO2NTs)修饰电极。分别采用扫描电子显微镜和X射线衍射对Ni/TiO2NTs电极的形貌及组分进行了表征。将Ni/TiO2NTs电极用于对胰岛素的电化学测定。结果表明,在0.1 mol/L NaOH支持电解液中,胰岛素在Ni/TiO2NTs电极上有较好的电化学响应,胰岛素浓度在0.8～1.6μmol/L范围内,峰电流密度与其浓度呈良好的线性关系,检测限为0.28μmol/L,灵敏度为0.49×10-3 A/(μmol·L-1.cm-2)。Highly ordered TiO2 nanotube arrays（ TiO2 NTs） fabricated by anodization were employed as a substrate and loaded with Ni nanoparticles by pulse electrodeposition. The morphology and composites of titanium dioxide nanotubes and Ni/TiO2 NTs electrodes were investigatel using scanning electron microscopy and energydispersive X-ray spectroscopy, respectively. The Ni/TiO2 NTs was used as an amperometric detector for electrocatalytic oxidation and determination of insulin. The results show that Ni/TiO2 NTs electrode enables the oxidative detection of insulin at this modified electrode. The linear dynamic range of the detection is 0. 8 - 1.6 μmol/L in 0. 1 mol/L NaOH electrolyte, with a good sensitivity （0. 49 x 10-3 A/（ μmol. L -1. cm-2） and low detection limit （0. 28 μmol/L）.

关 键 词：电化学 修饰电极 纳米镍 TIO2纳米管阵列 胰岛素 

分 类 号：O646[理学—物理化学]