同型半胱氨酸与急性冠脉综合征相关性  

The correlation of acute coronary syndrome and homocysteine

作　　者：刘利军[1] 张爱萍[2] 程自平[1] 

机构地区：[1]安徽医科大学第一附属医院心血管内科,安徽省合肥230022 [2]淮南市第一人民医院心血管内科

出　　处：《中国基层医药》2012年第13期1941-1942,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨同型半胱氨酸（Hcy）与急性冠脉综合征（ACS）相关性及冠脉介入治疗前后血清Hcy的变化。方法采用透射免疫比浊法，分别检测89例ACS组和28例冠状动脉正常组的Hcy水平，以及70例行冠脉支架植入术后的Hcy水平。结果ACS组的Hcy水平显著高于冠状动脉正常组（t=18．35、22．17，均P〈0．01）。不同冠脉病变支数Hcy水平差异均有统计学意义（t=10．87、2．34、2．31，均P〈0．01）。冠脉介入治疗前后Hcy差异无统计学意义（P〉0．05）。结论Hcy与ACS关系密切，检测其水平的变化，可反应ACS的发展进程及预后，为临床预防和治疗ACS提供可靠的依据。Objective To explore the correlation between coronary lesions and homocysteine and the plasma homocysteine changes before and after coronary intervention treatment. Methods By the transmission immune meth- od than turbidity, respectively, 89 patients with acute coronary syndrome test group and 28 coronary arterj of the nor- mal group Hcy level and 70 routine coronary stents after implantation of Hcy level. Results Acute coronary syndrome group of Hcy content was significantly higher than normal coronary artery （ P 〈 0.01 ）. Coronary lesions impact Hcy level,its significant difference（ P 〈 0.01 ）. And coronary intervention before and after treatment Hcy no significant differences （ P 〉 0.05 ）. Conclusion High homocysteine is cardiovascular disease of a new and important independ- ent risk factors. Hcy close relations with ACS, positively related, testing their level of change, and can be eJTfectively re- action to the development process of the ACS and prognosis, prevention and treatment for clinical ACS provide reliable basis. Coronary intervention treatment can reduce Hcy whether level and role of blood vessels,is yet to be studied further.

关 键 词：半胱氨酸 冠状动脉疾病 

分 类 号：R541.4[医药卫生—心血管疾病]