单纯手法复位与合并药物治疗良性阵发性位置性眩晕的疗效比较  

Epley′s manoeuvre versus Epley′s manoeuvre plus labyrinthine sedative in the management of benign paroxysmal positional vertigo:prospective,randomised study

作　　者：张慧[1] 耿曼英[1] 闫保星[1] 卢星[1] 

机构地区：[1]郑州大学第二附属医院耳鼻咽喉科,郑州450014

出　　处：《临床耳鼻咽喉头颈外科杂志》2012年第16期750-752,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:比较单纯手法复位与合并药物治疗良性阵发性位置性眩晕(BPPV)的疗效及复发情况。方法:对84例BPPV患者采取随机对照方法进行临床研究,对照组42例予单纯手法复位,治疗组42例在手法复位的基础上口服甲磺酸倍他司汀片、盐酸氟桂利嗪、金纳多滴剂。7d、28d后进行疗效评定,观察半年的复发情况。结果:治疗7d后,治疗组痊愈率为78.57%,总有效率为92.86%,均高于对照组(分别为50.00%和80.95%,P<0.05);治疗28d后,治疗组痊愈率为80.95%,总有效率为95.24%,与对照组(分别为71.43%和90.48%)比较无差异(P>0.05);随访半年,治疗组3例(7.14%)复发,对照组7例(16.67%)复发,两组差异有统计学意义(P<0.05)。结论:复位法治疗BPPV有效、简便、安全,可作为首选的治疗方法,配合药物综合治疗近期能缓解症状,缩短治愈时间。Objective：To compare the efficacy of Epley’s manoeuvre and Epley’s manoeuvre plus labyrinthine sedative in the treatment of benign paroxysmal positional vertigo.Method：Eighty-four patients with benign paroxysmal positional vertigo were included in a randomized study.Forty-two cases in control group were treated with Epley’s manoeuvre alone and the other 42 cases in treated group receivedEpley′s manoeuvre together with Betahistine Mesilate Tablets,Flunarizine Hydrochloride,and Extract of Ginkgo Biloba Leaves Tablets.Both groups were analyzed after one week and four weeks,and recurrence was observed after half a year.Result：After one week treatment,cure rate and total effective rate of treated group was higher than that of control group（78.57% vs 50.00% and 92.86% vs 80.95%,P〈0.05,respectively）.After four weeks treatment,there was no significant difference in cure rate and total effective rate between two groups（80.95% vs 71.43% and95.24% vs 90.48%,P〉0.05,respectively）.After half year,recurrence was found in 3 patients in treated group compared with 7 patients in control group（7.14% vs 16.67%）,and the difference was statistically significant（P〈0.05）.Conclusion：Epley′s manoeuvre is the best treatment method of benign paroxysmal positional vertigo together with the medicine.It is easy,safe and effective,and the healing time can be shortened.

关 键 词：良性阵发性位置性眩晕 手法复位 药物疗法 

分 类 号：R764.3[医药卫生—耳鼻咽喉科]