苦参碱葡萄糖注射液致水样腹泻  

Watery diarrhea induced by matrine and glucose injection

作　　者：顾生旺 蒋兆荣 

机构地区：[1]解放军第八二医院感染内科,淮安223001

出　　处：《药物不良反应杂志》2012年第3期177-178,共2页Adverse Drug Reactions Journal

摘　　要：1例55岁女性患者因肝癌、肝硬化静脉滴注苦参碱葡萄糖注射液250 ml,1次/d。次日出现水样腹泻,立即停药。第3天腹泻消失。间隔2 d后,患者再次静脉滴注苦参碱葡萄糖注射液250 ml,1次/d。第3天发生严重无痛性水样腹泻。给予大蒜素、诺氟沙星、复方地芬诺酯、头孢西丁,但腹泻无缓解。第4天停用苦参碱葡萄糖注射液。次日,腹泻停止。A 55-year-old female received an IV infusion of matrine and glucose injection 250 ml once daily for liver cancer and cirrhosis. The next day, she developed watery diarrhea, and matrine and glucose injection was stopped immediately. On day 3, diarrhea disappeared. Two days later, the patient was readministered an IV infusion of matrine and glucose injection 250 ml once daily. On day 3, she presented with severe painless watery diarrhea. Despite receiving garlicin, norfloxacin, compound diphenoxylate, and cefoxitin, her diarrhea did not improve. On day 4, matrine and glucose injection was discontinued. The following day, the patient＇s diarrhea resolved.

关 键 词：苦参碱 腹泻 

分 类 号：R595.3[医药卫生—内科学]