Active spot-scanning test with heavy ions at HIRFL-CSR  

作　　者：戴中颖 李强 刘新国 金晓东 黄齐艳 肖国青 

机构地区：[1]Institute of Modern Physics, Chinese Academy of Sciences [2]Graduate University of Chinese Academy of Sciences [3]Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences

出　　处：《Chinese Physics C》2012年第8期784-791,共8页中国物理C（英文版）

基　　金：Supported by National Basic Research Program of China(973Program,2010CB834203);the Key Project of National Natural Science Foundation of China(10835011);National Natural Science Foundation of China(10905080,11075191);the Natural Science Foundation of Gansu Province of China(1010RJZA007);Science and Technology Development Project of Lanzhou City(2008-sr-10,2009-2-12)

摘　　要：An active spot beam delivery system for heavy ion therapy has been developed based on the Cooling Storage Ring at HIRFL-CSR, where the pencil carbon-ion beams were scanned within a target volume transversely by a pair of orthogonal （horizontal and vertical） dipole magnets to paint the slices of the target volume and longitudinally by active energy variation of the synchrotron slice by slice. The unique techniques such as dose shaping via active energy variation and magnetic deflection constitute a promising three-dimensional conformal even intensity-modulated radiotherapy with heavy ions at HIRFL-CSR. In this paper, the verification of active energy variation and the calibration of steerable beam deflection are shown, as the basic functionality components of the active spot-scanning system. Additionally, based on the capability of creating homogeneous irradiation fields with steerable pencil beams, a radiobiological experiment like cell survival measurement has been performed aiming at comparison of the radiobiological effects under active and passive beam deliveries.An active spot beam delivery system for heavy ion therapy has been developed based on the Cooling Storage Ring at HIRFL-CSR, where the pencil carbon-ion beams were scanned within a target volume transversely by a pair of orthogonal （horizontal and vertical） dipole magnets to paint the slices of the target volume and longitudinally by active energy variation of the synchrotron slice by slice. The unique techniques such as dose shaping via active energy variation and magnetic deflection constitute a promising three-dimensional conformal even intensity-modulated radiotherapy with heavy ions at HIRFL-CSR. In this paper, the verification of active energy variation and the calibration of steerable beam deflection are shown, as the basic functionality components of the active spot-scanning system. Additionally, based on the capability of creating homogeneous irradiation fields with steerable pencil beams, a radiobiological experiment like cell survival measurement has been performed aiming at comparison of the radiobiological effects under active and passive beam deliveries.

关 键 词：spot-scanning heavy ion radiotherapy beam delivery active energy variation 

分 类 号：O571.6[理学—粒子物理与原子核物理]